About this Research Topic
The coronavirus disease 2019 pandemic has been a phenomenon with tremendous strength unfolding in waves, representing a rapidly spreading infectious disease, that affected heavily individual persons, local communities, societies and healthcare systems. Health and economic sequalae of COVID 19 pandemic are still evident impacting individual health and healthcare systems despite the relatively rapid development of effective vaccines.
Central in the COVID – 19 disease manifestations, stands its impact on the cardiovascular system leading to a variety of cardiovascular complications that occur in over 20% of hospitalized patients in various registries. Myocardial injury identified by a rise in hs troponin levels confers a worse prognosis in hospitalized patients and is a much more common finding than true myocarditis diagnosed by current clinical, biochemical and imaging criteria. Echocardiography with the integration of strain imaging is the primary modality in diagnosing and monitoring cardiovascular complications while the use of parametric CMR indices may facilitate myocarditis diagnosis. Distinguishing between the different mechanisms of myocardial injury with the integration of multiple clinical, biochemical and imaging criteria may lead to a more individualized approach in treating and monitoring patients for the longer term impact of myocardial involvement in Covid 19 disease.
This research topic will explore diagnostic criteria, actual prevalence and long term sequelae of COVID 19 myocarditis in relation to patients’ groups with different baseline clinical characteristics and predisposing factors, as well as promote research on novel biochemical, imaging and clinical biomarkers. It is also within the goal of this Research Topic to explore data on COVID -19 myocarditis and myocardial injury after the first wave of the pandemic in relation to different viral mutations and genetic variability.
This Research Topic will accept manuscripts related to this area of research aiming to focus on various markers to distinguish between different types of myocardial injury, placing an emphasis on the diagnosis of COVID 19 myocarditis. Moreover, data on the longer- term follow up and prognosis of patients with concomitant myocardial injury will be of great interest.
Sub-topics include but are not limited to:
- Echocardiographic, CMR markers and possibly PET markers of COVID -19 myocarditis compared to type II myocardial infarction
- Comparative data on COVID 19 myocarditis or myocardial injury between the first and the subsequent pandemic waves
- Novel biochemical markers, micro–RNAs in the diagnosis of COVID -19 myocarditis
- Prognostic imaging markers for COVID - 19 related myocardial injury
Central in the COVID – 19 disease manifestations, stands its impact on the cardiovascular system leading to a variety of cardiovascular complications that occur in over 20% of hospitalized patients in various registries. Myocardial injury identified by a rise in hs troponin levels confers a worse prognosis in hospitalized patients and is a much more common finding than true myocarditis diagnosed by current clinical, biochemical and imaging criteria. Echocardiography with the integration of strain imaging is the primary modality in diagnosing and monitoring cardiovascular complications while the use of parametric CMR indices may facilitate myocarditis diagnosis. Distinguishing between the different mechanisms of myocardial injury with the integration of multiple clinical, biochemical and imaging criteria may lead to a more individualized approach in treating and monitoring patients for the longer term impact of myocardial involvement in Covid 19 disease.
This research topic will explore diagnostic criteria, actual prevalence and long term sequelae of COVID 19 myocarditis in relation to patients’ groups with different baseline clinical characteristics and predisposing factors, as well as promote research on novel biochemical, imaging and clinical biomarkers. It is also within the goal of this Research Topic to explore data on COVID -19 myocarditis and myocardial injury after the first wave of the pandemic in relation to different viral mutations and genetic variability.
This Research Topic will accept manuscripts related to this area of research aiming to focus on various markers to distinguish between different types of myocardial injury, placing an emphasis on the diagnosis of COVID 19 myocarditis. Moreover, data on the longer- term follow up and prognosis of patients with concomitant myocardial injury will be of great interest.
Sub-topics include but are not limited to:
- Echocardiographic, CMR markers and possibly PET markers of COVID -19 myocarditis compared to type II myocardial infarction
- Comparative data on COVID 19 myocarditis or myocardial injury between the first and the subsequent pandemic waves
- Novel biochemical markers, micro–RNAs in the diagnosis of COVID -19 myocarditis
- Prognostic imaging markers for COVID - 19 related myocardial injury
Keywords: COVID, Cardiovascular Complications, Myocarditis, Myocardial Injury
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
