About this Research Topic
The goal is to bring together the latest original research, reviews, opinions, and perspectives on neurosteroids and the translation of their basic research into clinical practice, particularly though not exclusively in the context of traumatic brain injury, stroke, and neurodegeneration. The overall goal is to stimulate more interest along with new findings on neuroprotection and repair of both the central and peripheral nervous systems. Since little progress has been made in finding safe and effective treatments for traumatic brain injury, stroke, and degenerative disorders, it is hoped that this Research Topic will aid in that endeavor.
We welcome work focused but not limited to the following areas:
• Sex differences, aging, and other treatment variables in response to progesterone and allopregnanolone in health and disease
• Latest developments in the use of progesterone, allopregnanolone, and their derivatives in the treatment of CNS and peripheral injuries
• Neurosteroids as potential treatments for age-related degenerative disorders: basic and translational research
• How current research can improve the success rate of clinical trials in neuroprotection and repair
Keywords: Neuroprotection, Brain, spinal cord, traumatic brain injury, Stroke, optic nerve damage, Alzheimer’s disease, progesterone, allopregnanolone, Nestorone, recovery of function, neurosteroids
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.