About this Research Topic
During the last 25 years, heightened concerns over allergy have seen greater emphasis being placed on allergy risk assessment by regulators prior to the introduction of novel foods and feeds and associated novel proteins.
Novel foods/feeds protein allergy assessment is the product of a weight-of-evidence and employs a broad range of disciplines including data science, biological sciences, and qualitative/quantitative risk assessment.
In this Research Topic, a series of manuscripts entailing application of scientific methods and assessment approaches for protein allergy assessment will be assembled. The challenge is that allergy research is very diverse and dispersed across a mix of academic, medical and research centers. This Research Topic aims to construct a view of what has been learned over the last 25 years since commercial novel protein products have come to the market and globalization has dispersed more novel foods.
Suitable themes for manuscripts include, but are not limited to:
• Defining the scientific challenges for assessing and predicting protein allergens
• Novel doesn’t necessarily mean novel in function and/or structure: defining “novel” is a key aspect of understanding protein allergy risk. How can this be done with better accuracy and precision?
• A key part of safety assessments relies on bioinformatics and the application of mathematical approaches to understanding allergy risk: what are the advancements that have been made in 25 years?
• Sensitization and exposure risk to novel foods/feeds/proteins is difficult to quantify: how have we gotten closer to quantitative risk assessments?
• Defining the research gaps and future needs for allergy safety and allergen prediction
All article types accepted by Frontiers in Allergy are welcome.
Keywords: Sensitization, Elicitation, Bioinformatics, Predictive, Risk, Allergy, Safety, Food Allergy
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.