About this Research Topic
This Research Topic aims to explore the role of intestinal models in nutrient science, focusing on their application in clinical research and their potential to simulate organism-level interactions. Key questions include the effectiveness of nutrient conversion and absorption models and the adequacy of organ-on-chip models for comprehensive studies. By investigating these areas, the research seeks to validate and enhance the use of artificial intestine simulators, organ-on-chip, and in silico models, ultimately contributing to a deeper understanding of nutrient metabolism and absorption.
To gather further insights into the capabilities and limitations of these models, we welcome articles addressing, but not limited to, the following themes:
- Development and validation of artificial intestine models
- Comparative studies of nutrient absorption models using host cell lines and tissues
- Integration of microbiota in nutrient metabolism models
- Applications of organ-on-chip models in nutrient research
- Impact of diet, drugs, and disease on intestinal models
- Ethical considerations and experimental design improvements in nutrient research
- Advances in in silico modeling for nutrient absorption and metabolism
Keywords: organ-on-chip, nutrition, methodology, intestine, model, modelling, nutrient adsorption, gut microbiota, artificial intestine, simulators, Artificial intestine models, Nutrient digestion, Enzyme secretion, digestive environment, nutrient interactions
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.