Material depletion and environmental impacts implied the adoption of biomass as renewable sources for bulk and pharmaceutical chemicals. The 7th principle of green chemistry encourages the switch from a fossil to a bio-based industry to reduce burdens and minimize the waste generation. This sector of bio-based chemicals is considered among the most investigated research fields and has changed during the last two decades. Recent ambition of developing a climate neutral society seems in line with the possibility of using non-dedicated vegetable biomass to absorb carbon dioxide and stock it, at least until entering the end of life stage.

In line with the scope of promoting a Green and Sustainable Chemistry, there is the necessity to collect and share innovation on new products, techniques, sources and evaluation strategies of the greenness grade associated with products from biorefinery. In particular, research works on the following principal bio-based chemicals are welcome: Levulinic acid, 2,5-Furan dicarboxylic acid, Mono-ethylene glycol, Methyl vinyl glycolate, p-xylene, Propylene glycol, Epichlorohydrin, 1,3-Propanediol 3-Hydroxypropion aldehyde, Acrylic acid, Propylene, Itaconic acid, Adipic acid, 3-Hydroxypropionic acid / aldehyde, Isoprene/farnesene, Glutamic acid, Aspartic acid, 1,4-butanediol, Maleic anhydride, Polylactic acid and Polyurethanes.

This Research Topic on “Biorefinery chemicals: trend, sources and metrics” aims to cover promising and novel advances in this field by addressing new challenges within the most consolidated and used bio-based products worldwide. The Editors welcome Original Research, Review, Mini Review and Perspective articles on themes including, but not limited to:

• Recent trend and innovation in catalyst
• New reaction conditions, reactor type and solvents used
• Innovative analytical methods, separation and purification strategies
• Main feedstock used worldwide (trend ad efficiency)
• Dedicated vs marginal biomass
• Waste valorisation in a circular business ecosystem
• Re-thinking processes for substrate recovery
• Assessment of the greenness grade at laboratory and process scale through green metrics.

Manuscripts concerning the application of the LCA (Life Cycle Assessment) methodology are out the scope of such Research Topic.

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