Oxidative stress (OS) in the human body is due to an imbalance between the antioxidant system and the generation of reactive oxygen (ROS) and nitrogen species (RNS). The consequence of high disturbances of redox homeostasis is impaired intra- and intercellular signalling pathways controlled by redox processes and/or damage to molecules induced by overproduction of ROS and RNS. These OS markers are generated both in muscle fibres during rest and their production is increased during muscle contraction. Exercise-induced oxidative stress (EIOS) could be harmful to health and is associated with oxidant damage to macromolecular structures and accelerated muscular fatigue. The antioxidative enzymes are an important antioxidant defense line. On the other hand, exercise-induced overproduction of ROS in skeletal muscle can also play a vital role in skeletal muscle adaptations to the different types of high intensity exercise training particularly endurance training. Amount of disruption in the redox homeostasis depends on, among others, the duration and intensity of the effort, the level of antioxidants, nutritional, and physiological status and there may be sex differences in men and women.

All questions related to EIOS are welcome in this Research Topic. The aim of this Research Topic is to provide the article collection that promotes the scientific knowledge and insights into EIOS and the role of antioxidant supplementation in sport and exercise.

We accept papers that elucidate the:
• Effects of duration and exercise intensity on EIOS
• Sex differences in EIOS
• Effects of antioxidant supplementation and nutrition on EIOS
• Age-related changes in exercise-induced oxidative stress
• Acute and chronic effects of various physical trainings on OS
• Impact of timing antioxidant supplementation on EIOS
• Non-invasive measurement of EIOS
• Role of EIOS in physiological responses and adaptations

Articles can be placed either in Frontiers in Sports and Active Living; Frontiers in Physiology or in Frontiers in Nutrition.

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