Clinical procedures to treat hard and soft tissue defects resulting from periodontal disease, congenital or acquired pathologies, or maxillofacial trauma, sometimes rely upon mass-produced biomaterials created for a variety of surgical indications, however, additive manufacturing (ie, 3d printing and electrospinning) represents a paradigm shift in manufacturing at the individual patient level and are currently of particular interest. Additive manufacturing is the automated fabrication of 3D structures through the successive layer-by-layer deposition of biomaterials. Today large numbers of synthetic materials, such as bioceramics, polymers, and their composites, have been extensively developed using additive manufacturing for the repair and reconstruction of oral tissues. This Special Issue aims to present some of the best research currently performed on the additive manufacturing of biomaterials in regenerative dentistry.

The treatment of dental, oral, and craniofacial bone defects is currently restricted by available biomaterials, which have limited capacity to facilitate the true regeneration of new tissues that exhibit native physiologic form, function, and esthetics. A major focus of research must be on optimizing additive manufacturing for producing bioresorbable scaffolds that can reliably and safely reconstruct bony defects. Further, there exists tremendous potential in functionalizing scaffolds for therapeutic purposes. Additive manufacturing offers a promising future in which the development of superior sustainable regenerative biomaterials will be accessible to the general public. Adapting additive manufacturing technology for bone tissue engineering will allow dentists to explore new regenerative possibilities, thus increasing treatment options for patients and improving their oral health. It will eventually become a new standard of care for patients to construct personalized bone constructs for dental regenerative medicine.

The topics of interest include (but are not limited to):
- Additive manufactured (i.e., 3D printed and electrospun) scaffolds, implant and, prosthetics
- Tissue and organ printing
- drugs and drug delivery systems developed using additive manufacturing
- Pre- and post- functionalization/processing/treatment of additive manufactured biomaterials including surface bio-functionalizations and coatings
- Patient-specific solutions enabled by additive manufacturing
- Indirect additive manufacturing and hybrid manufacturing techniques, and other novel fabrication procedures applied to biomaterials.
- Biological and clinical performance evaluation of additive manufactured biomaterials

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