Nutraceuticals has been classified according to their natural sources, pharmacological characteristics, or based on their chemical composition. According to the Food and Drug Administration and European Food safety authority, they should contain vitamins, minerals, herbs, amino acids, concentrates, metabolites, or extracts. In addition to those derived from plants, more recently compounds from marine organisms are increasingly studied. Evidence is growing on the relation between nutraceuticals and lipid metabolism, with implication in physiological processes and pathophysiological conditions such as obesity, diabetes, metabolic syndrome, regulation of energy intake/expenditure and dietary habits. Moreover, biological effects of nutraceuticals, targeting lipid profile, involve also the interplay of gut microbiota and derived metabolites with digestive processes and implications in health or diseases.

The main goal of this Research Topic is to improve the knowledge on the role and mechanisms of nutraceuticals and functional foods from in vitro and in vivo studies in cell signaling, gene expression, cell/tissue functions, microbiome, metabolome and variation in effects due to gene polymorphisms related to lipid metabolism and profile.

This Research Topic is intended to provide readers the basic research on the regulatory mechanisms of nutraceuticals in lipid metabolism. We welcome Original research, Review, Mini-Review, Short communications and Perspectives articles that are related, but not limited to the following subtopics:

• Effect on adipogenesis, lipolysis and energy expenditure

• Natural compounds on white adipose tissue browning

• Role of nutraceuticals in potential therapeutic strategies to target lipid metabolism and cardiometabolic diseases

• Nutraceuticals and lipidome

• Nutrigenomic impact on lipid targets

• Nutraceutical effects on gut microbiome, and related interactions with heart, brain and other tissues, with implication for health and diseases.

• Genetic determinants of nutraceutical impact on lipid profile

• Functional food in metabolic dysfunction

Submit your idea

Impact

Frontiers in Physiology

Participating Journals

Impact