Tissue engineering and regenerative medicine have developed rapidly in recent years. More and more regenerative approaches have been applied to clinical practice; such as heart diseases, and trachea transplants. However, difficulties are still present in the self-healing of cartilage/meniscus defects. According to the 2018 WHO Global Burden of Disease Study, approximately 303 million people suffered from osteoarthritis (OA) from 1990 to 2017. Moreover, most of these patients have suffered from cartilage/meniscus injuries. Hence, it is of great necessity to develop novel approaches to treat this defect. Thankfully, tissue engineering and regenerative medicine brings new hope to this.

Biomaterials play a critical role in the development of cartilage/meniscus tissue engineering and regeneration. However, research needs to continue to progress in the fields of biomaterials, stem cells, biofabrication, gene therapy, drug delivery, and other relevant science to further advance the science behind this. This collection presents an opportunity for scientists to share their recent and significant biomaterials research progress.

In this Research Topic, we aim to recruit manuscripts that focus on novel biofabrication approaches for cartilage/meniscus regeneration, the advanced biomaterials for cartilage/meniscus regeneration, or the new strategies and the potential regenerative mechanism for cartilage/meniscus regeneration. These themes include, but are not limited to, the following:

• Novel biofabrication approach for the cartilage/meniscus regeneration, such as novel 3D printing technique, electrospinning methods, or bio-ink advance, et al.
• Advanced biomaterials for cartilage/meniscus regeneration, such as new control released drugs, novel bioactive peptides, et al.
• New strategies for cartilage/meniscus regeneration, such as cell-free strategies, cell-based strategies, gene therapy approaches, immune-regulation-based strategies, et al.
• Potential regenerative mechanism for cartilage/meniscus regeneration.
• Preclinical research or clinical trial for cartilage/meniscus regeneration.

Submit your idea

Impact

Frontiers in Bioengineering and Biotechnology

Participating Journals

Impact