About this Research Topic
Biosensing devices such as lateral flow assays or blood glucose test strips have had an important role in healthcare for more than half a century and have already improved our living standards. In particular, biosensors allow us to measure clinically relevant biomarkers from various sample matrices (including whole blood, plasma, saliva, or urine) in a fast, cost-effective, and user-friendly manner. Hence, biosensing technology can provide vital information related to the propensity for illness or the status of a disease or its treatment. However, there are still some challenges especially regarding the sample collection and preparation as well as biosensing performance.
To further assess the potential of this technology, researchers are pushing forward the frontiers of integrated biosensors, combining the sample collection, preparation, analysis, and data evaluation, to create “sample-in-answer-out” diagnostic devices. Such integrated solutions for biosensing could enable real-time, smart, sustainable, interoperable, and portable quantification of various biomolecules within clinically relevant body fluids in a superior fashion.
This Research Topic will be devoted to innovative approaches for integrated biosensing systems with potential applications in clinical and point-of-care settings. Areas to be covered in this Research Topic may include, but are not limited to:
● Biosensors using novel biorecognition elements
● Integrated biosensing devices for blood-based testing
● Integrated biosensors for non-invasive testing
● Wearable biosensing devices
● Smart technologies for biosensing
● Data transmission and evaluation technologies for biosensors
● Disposable (i.e., low-cost and calibration-free) - yet sustainable biosensors
● Biosensing devices for on-site testing
● Clinical applications of biosensors
The proposed biosensing approach should be demonstrated to be technically sound. Its analytical characterization in terms of accuracy (i.e., precision and trueness), sensitivity (i.e., limit-of-detection and/or limit-of-quantification), as well as selectivity, should be clearly studied and discussed.
Perspectives, (Mini) Reviews, Methods, Brief Research Reports, Technology and Code, and Original Research Articles will be considered for publication.
To further assess the potential of this technology, researchers are pushing forward the frontiers of integrated biosensors, combining the sample collection, preparation, analysis, and data evaluation, to create “sample-in-answer-out” diagnostic devices. Such integrated solutions for biosensing could enable real-time, smart, sustainable, interoperable, and portable quantification of various biomolecules within clinically relevant body fluids in a superior fashion.
This Research Topic will be devoted to innovative approaches for integrated biosensing systems with potential applications in clinical and point-of-care settings. Areas to be covered in this Research Topic may include, but are not limited to:
● Biosensors using novel biorecognition elements
● Integrated biosensing devices for blood-based testing
● Integrated biosensors for non-invasive testing
● Wearable biosensing devices
● Smart technologies for biosensing
● Data transmission and evaluation technologies for biosensors
● Disposable (i.e., low-cost and calibration-free) - yet sustainable biosensors
● Biosensing devices for on-site testing
● Clinical applications of biosensors
The proposed biosensing approach should be demonstrated to be technically sound. Its analytical characterization in terms of accuracy (i.e., precision and trueness), sensitivity (i.e., limit-of-detection and/or limit-of-quantification), as well as selectivity, should be clearly studied and discussed.
Perspectives, (Mini) Reviews, Methods, Brief Research Reports, Technology and Code, and Original Research Articles will be considered for publication.
Keywords: Integrated Biosensors, Sample Preparation, Microfluidics, Non-Invasive, Invasive, Diagnostics, Point-of-Care Testing, Wearables
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