About this Research Topic
The goal of the collection is to highlight works in multimodal imaging combining 1H-MRS and other imaging methods (DWI, fMRI, PET, EGG, etc.) in the study of healthy and pathological aging, with a focus on identifying novel biomarkers and correlates of cognitive decline. The specific aims of the Research Topic are, in order of importance, 1) to assess relationships between 1H-MRS neurochemistry and cognitive decline in healthy and pathological aging, 2) to assess possible relationships with 1H-MRS and measures of inflammation, brain energetics, cerebral connectivity and blood flow, and 3) to identify future directions in MRS and multimodal imaging in the study of aging.
Therefore, the types of articles that will be prioritised in the Research Topic are:
• Original research; in MRS or multimodal imaging with MRS in healthy or pathological aging.
• Reviews; in MRS in healthy or pathological aging, with a preference for AD/MCI, inflammation, cerebral blood flow, general cognition, as additional subtopic (one of these).
• Methods; providing technical outlines for MRS-based multimodal imaging in the study of healthy or pathological aging.
The Guest Topic Editors are indebted to the critical contribution made by William Vallet in coordinating the launch of this Research Topic.
Keywords: MR Spectroscopy, Aging, Metabolics, Cognitive Decline, Multi-modal Imaging
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.