About this Research Topic
In recent years, the medicinal use of cannabis and its derivatives has generated much interest as a potentially new pharmacological group that may prove the long awaited “game-changer” in chronic pain management. However, while public opinion and clinical practice seem to be growing more and more favourable to this idea, the scientific and clinical study of cannabinoids is still very much in its infancy.
The goal of this research topic is to present the latest basic and clinical research into cannabinoids as clinical tools in managing patients with pain. We aim to advance our current scientific concepts and introduce new evidence for the use of cannabinoids in pain management, as well as address major existing gaps, and by doing so promote more informed and accurate care for patients.
Accordingly, this research topic will include research articles, reviews and perspectives in medical cannabis research across various disciplines, ranging from basic and pre-clinical research on cannabinoids relevant to pathophysiological mechanisms underlying pain and nociception, to current clinical medical uses, as well as novel emerging technologies in the field of medical cannabis.
Overall, all subjects related to the potential role of cannabinoids in current pain management are a welcome addition to this research topic. Special focus will be given (but is not restricted) to:
• Randomized controlled trials
• Real-world large cohort studies
• Basic pharmacokinetics and pharmacodynamics of different cannabinoids and studies on the clinical pharmacology of cannabinoids across different disease states.
• Dosing regimens in different clinical settings and the relation between measured blood levels and therapeutic effects
• Cannabinoids in special populations – elderly and paediatric, psychiatric co-morbidities, opiate addiction etc.
• Side effects of cannabinoids, especially long term side effects, and information regarding drug-drug interactions
• Neural mechanisms of cannabis induced analgesia
• Technological innovations – manufacturing, delivery methods, improving patient monitoring and care
The goal of this research topic is to present the latest basic and clinical research into cannabinoids as clinical tools in managing patients with pain. We aim to advance our current scientific concepts and introduce new evidence for the use of cannabinoids in pain management, as well as address major existing gaps, and by doing so promote more informed and accurate care for patients.
Accordingly, this research topic will include research articles, reviews and perspectives in medical cannabis research across various disciplines, ranging from basic and pre-clinical research on cannabinoids relevant to pathophysiological mechanisms underlying pain and nociception, to current clinical medical uses, as well as novel emerging technologies in the field of medical cannabis.
Overall, all subjects related to the potential role of cannabinoids in current pain management are a welcome addition to this research topic. Special focus will be given (but is not restricted) to:
• Randomized controlled trials
• Real-world large cohort studies
• Basic pharmacokinetics and pharmacodynamics of different cannabinoids and studies on the clinical pharmacology of cannabinoids across different disease states.
• Dosing regimens in different clinical settings and the relation between measured blood levels and therapeutic effects
• Cannabinoids in special populations – elderly and paediatric, psychiatric co-morbidities, opiate addiction etc.
• Side effects of cannabinoids, especially long term side effects, and information regarding drug-drug interactions
• Neural mechanisms of cannabis induced analgesia
• Technological innovations – manufacturing, delivery methods, improving patient monitoring and care
Keywords: Medical Cannabinoid, Pain Management
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
