About this Research Topic
Balanced diets can improve human health, prevent the occurrence and development of many diseases, and prolong life spans. The intestinal microbiota homeostasis regulation provides new possibilities for the brain nutrition function of dietary polysaccharides, which be considered cannot pass through the blood-brain barrier in the past. Numerous studies have shown that many natural polysaccharides can enrich the diversity of intestinal flora. However, those polysaccharides may not be able to improve learning and memory function. Most of the existing studies focus on the influences of crude polysaccharide mixtures on the diversity and abundance changes of intestinal flora. The active components, structure-activity relationships, especially the molecular mechanism of dietary polysaccharides promoting brain health are not yet clear.
With this Research Topic, we wish to highlight the effects of diet, especially natural polysaccharides, on brain cognitive function, as well as to explore their potential mechanisms that how dietary polysaccharides can establish effective connections in the gut-brain axis, and ultimately improve brain health. This Research Topic is designed to promote an interdisciplinary approach to understanding the nutritional foundations of cognitive neuroscience.
We welcome all Original Research articles, Review, Perspectives, and Method focus on, but are not limited to, the following theme:
- Systematic exploration of the pathways, biomarkers and molecular mechanisms of how dietary polysaccharides affect brain cognitive function.
- The molecular mechanism of polysaccharide metabolites on brain cell metabolism, immune function, neuroplasticity and cognitive-related target proteins.
- Investigating how the active components and structure-activity relationships of dietary polysaccharides (within the range of dietary intake) affecting brain nutrition/cognitive function.
- The difference analysis and/or potential mechanism study of different natural polysaccharides that have been proved able to precisely regulate intestinal microbiota composition (including under different physiological conditions), thereby affecting brain function.
With this Research Topic, we wish to highlight the effects of diet, especially natural polysaccharides, on brain cognitive function, as well as to explore their potential mechanisms that how dietary polysaccharides can establish effective connections in the gut-brain axis, and ultimately improve brain health. This Research Topic is designed to promote an interdisciplinary approach to understanding the nutritional foundations of cognitive neuroscience.
We welcome all Original Research articles, Review, Perspectives, and Method focus on, but are not limited to, the following theme:
- Systematic exploration of the pathways, biomarkers and molecular mechanisms of how dietary polysaccharides affect brain cognitive function.
- The molecular mechanism of polysaccharide metabolites on brain cell metabolism, immune function, neuroplasticity and cognitive-related target proteins.
- Investigating how the active components and structure-activity relationships of dietary polysaccharides (within the range of dietary intake) affecting brain nutrition/cognitive function.
- The difference analysis and/or potential mechanism study of different natural polysaccharides that have been proved able to precisely regulate intestinal microbiota composition (including under different physiological conditions), thereby affecting brain function.
Keywords: Dietary polysaccharides, Cognitive function, Intestinal flora, Metabolites, Structure-activity relationship, Molecular mechanism
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
