About this Research Topic
Cervical cancer is the fourth most common occurring cancer in women with over 500,000 new cases globally in 2018. This has led to one of the major causes of cancer-related mortality globally. There has been a great development in preventive and screening measures, however the prognosis and 5-year overall survival rate of advanced cervical cancer remains to be poor. Therefore, further studies are required to help improve the survival outcome for patients.
Cervical cancer is typically treated with a combination of targeted therapies and surgical treatment. Radical hysterectomy is the most common form of surgical treatment in the early-stage cases of cervical cancer. There have been other forms of surgical treatment including laparotomy which has increased since the 2000s and was generally found to be used in early-stage cervical cancer cases. Some patients with relapsed cervical cancer have been treated with a rare surgical treatment known as Laterally Extended Endopelvic Resection (LEER) used to treat the pelvic sidewall recurrence of cervical cancer.
This Research Topic aims to provide insight in the comparison of various surgical treatments of cervical cancer and how they can influence the prognosis and survival outcome. Topics of interest include:
-Comparison of surgical treatment in cervical cancer
-Role of neoadjuvant chemotherapy: comparison between different regimens; predictive factors of activity and outcomes in cervical cancer
-The role of radiation therapy in cervical cancer
-Radical hysterectomy
-Minimally invasive surgery
-Laterally extended endopelvic resection
-Translational medicine in the surgical field
-Molecular indices for predicting the response to neoadjuvant therapy for the modulation of surgery
Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.
Cervical cancer is typically treated with a combination of targeted therapies and surgical treatment. Radical hysterectomy is the most common form of surgical treatment in the early-stage cases of cervical cancer. There have been other forms of surgical treatment including laparotomy which has increased since the 2000s and was generally found to be used in early-stage cervical cancer cases. Some patients with relapsed cervical cancer have been treated with a rare surgical treatment known as Laterally Extended Endopelvic Resection (LEER) used to treat the pelvic sidewall recurrence of cervical cancer.
This Research Topic aims to provide insight in the comparison of various surgical treatments of cervical cancer and how they can influence the prognosis and survival outcome. Topics of interest include:
-Comparison of surgical treatment in cervical cancer
-Role of neoadjuvant chemotherapy: comparison between different regimens; predictive factors of activity and outcomes in cervical cancer
-The role of radiation therapy in cervical cancer
-Radical hysterectomy
-Minimally invasive surgery
-Laterally extended endopelvic resection
-Translational medicine in the surgical field
-Molecular indices for predicting the response to neoadjuvant therapy for the modulation of surgery
Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.
Keywords: surgery, cervical cancer, gynecology
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
