Given the success of Volume I of this Research Topic, and the rapidly evolving subject area, we are pleased to announce the launch of this Volume II.

Studies of several factors and hazardous substances that could affect human microbiota eubiosis would benefit from a more multidisciplinary approach. The outcome of such approach could hugely contribute to the clinical and convergent basic health research area. Therefore, interaction and collaboration among distinct scientific disciplines such as microbiology, nutrition, toxicology and personalized medicine, as well as involvement of multiple technologies, communities and professional domains, are needed to obtain relevant outcomes.

The main objective of this Research Topic is to compile the upmost scientific information about human microbiota variability linked or affected by diet hazardous substances exposure and consumption. Moreover, studies that analyse the ability of modulation or intervention with nutraceuticals or probiotics in order to recover from this physiological imbalanced status would be a relevant asset to the collection.

To gather relevant data showing holistic analysis of human microbiota as a metabolic node for health impact is our ultimate goal. Furthermore, we hope to compile multiple studies supporting the elucidation of the key role of human microbiota in new common multifactorial imbalanced metabolism caused by exposure to hazardous substances.

Contributions submitted by research teams should be concerning following themes:
• food risk assessment in relation to human microbiota, metabolome, and endocrine disruptors;
• link between hazardous dietary substances and obesity, insuline resistance, cardiovascular and metabolic syndrome, infertility;
• impact of probiotics, interventions, omics technologies.

Dr. Els Van Pamel, one of the guest editors of this Research Topic, attends progress meetings of a project in which a commercial company conducts research on the impact of nutraceuticals on gut health, giving scientific advice. She is not employed by the company nor payed on budget of the project.

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