About this Research Topic
The current Research Topic aims to discover bioactive natural products from microbes as drug leads, using new technologies such as metagenomics and gene mining to look for the breakthrough of new drug research and development. In light of the current clinical drug needs, integrating technologies and methods of microbiology, genomics, natural medicinal chemistry, pharmacology, synthetic biology, etc, focusing on the areas of drug discovery, activity evaluation, structure modification and biogenic synthesis, yield improvement of bioactive products. The research on new sources of microbial resources to expand the existing microbial pool, is promoting the development of innovative drugs.
We welcome submissions of different types of manuscripts including Original Research articles and Reviews, including but not limited to:
• Isolation, structure elucidation and biological activities of novel microbial natural products from unique ecological niche.
• Investigation of active compounds after genetic mining or engineering.
• Biosynthesis of diverse microbial secondary metabolites.
• Structure modification for improvement of lead compounds.
All the manuscripts submitted to the collection will need to fully comply with the Four Pillars of Best Practice in Ethnopharmacology (you can freely download the full version here
Keywords: Natural Product, Microbe, Structure elucidation, Activity evaluation, Biosynthesis
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.