About this Research Topic
The endovascular treatment option of cerebral aneurysm includes intrasaccular coil embolization with or without stent or balloon support. The endovascular treatment of wide-necked, giant, fusiform, dissecting, blister aneurysms represents a challenging problem in traditional techniques. Moreover, some small (≤7mm) and most very small (≤3mm) aneurysms are usually not amenable to coil embolization. The recent development of endovascular techniques/devices has provided interventionalists with the ability to treat such challenging aneurysms safely. Flow diversion is an endovascular technique where, instead of filling the aneurysm sac with coils, a metallic mesh stent is placed in the parent vessel across the aneurysm neck to reconstruct the vessel wall. The so-called flow diverting stent (FDS) differs from traditional stents in that it has very small strut size (around 200 micrometers) so as to divert blood flow away from the aneurysm, thus encouraging thrombosis within the aneurysm.
FDS has been increasingly used since its first introduction to neurointerventionalists. 10 years have passed, and some unsolved problems and debated issues remain about FDS treatment. Moreover, FDS has three times more metallic load when compared to traditional intracranial stent; it necessitates therefore cautious use of antiaggregant medication. Also, its useability in ruptured aneurysms is still speculative. This Research Topic will deal with all types of discussion in the endovascular treatment of intracranial aneurysm, with special reference to FDS usage.
Editors of this Research Topic will welcome submissions about, but not limited to:
• The treatment of all types of intracranial aneurysm, such as giant, blister, recurrent, saccular, ruptured-unruptured, sidewall-bifurcation, with the special reference to treatment with FDS
• Recent advances in medication after FDS, including different loading strategies, maintenance, intraoperative salvage medication, information about drug resistance, and onsite monitoring devices for drug resistance
• Hemorheological effects of FDS by using CFD analysis
• Possible pathophysiologic mechanisms responsible for late intracranial bleeding, a most dangerous complication after FDS treatment
• Clinical and if possible, animal studies
• Reviews, invitro and/or clinical research, and opinion articles are also welcome
FDS has been increasingly used since its first introduction to neurointerventionalists. 10 years have passed, and some unsolved problems and debated issues remain about FDS treatment. Moreover, FDS has three times more metallic load when compared to traditional intracranial stent; it necessitates therefore cautious use of antiaggregant medication. Also, its useability in ruptured aneurysms is still speculative. This Research Topic will deal with all types of discussion in the endovascular treatment of intracranial aneurysm, with special reference to FDS usage.
Editors of this Research Topic will welcome submissions about, but not limited to:
• The treatment of all types of intracranial aneurysm, such as giant, blister, recurrent, saccular, ruptured-unruptured, sidewall-bifurcation, with the special reference to treatment with FDS
• Recent advances in medication after FDS, including different loading strategies, maintenance, intraoperative salvage medication, information about drug resistance, and onsite monitoring devices for drug resistance
• Hemorheological effects of FDS by using CFD analysis
• Possible pathophysiologic mechanisms responsible for late intracranial bleeding, a most dangerous complication after FDS treatment
• Clinical and if possible, animal studies
• Reviews, invitro and/or clinical research, and opinion articles are also welcome
Keywords: Cerebral aneurysms, Endovascular techniques, Embolization, Flow diverting stents, Antiaggregant treatment
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
