About this Research Topic
This Research Topic aims to highlight research on natural products specifically compounds including; terpenes, flavonoids, alkaloids and phytoestrogen and their cancer preventive characteristics. We ask authors to sufficiently detail the composition, stability, antiangiogenic potential and/or antitumoral action of these biomolecules. Research may include natural products derived from biological sources with some chemical modifications. Antitumoral modalities of natural products can be demonstrated using in-vivo models. This must be supported in at least two well-authenticated cancer cell lines (ideally originating from distinct organs/tissues). Submissions dealing with antiangiogenic potential must describe the mechanism of action and molecular targets (factors, cytokines, receptors, signaling pathway), besides their chemical structure class. Areas of interest for this Topic include:
- Scientific evidence in vitro and/or in vivo or pre-clinical studies which attracts pharmaceutical interest.
- Research which promotes large scale development relevant for clinical cancer treatment protocols such as single drug or in combination with other drugs or antitumor strategies, such as immunotherapy
- Studies focusing on statistical analysis (not epidemiological) referring to the traditional use of natural compounds in a given region as a preventive factor in the face of cancer development.
Keywords: Natural Products, Antitumoral, Antiangiogenic, New drugs, Mechanisms of action
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.