About this Research Topic
The application of neoantigens is rapidly becoming more widespread in clinical settings; not only just related to the development of tumor vaccine or adoptive cell therapy but also in the monitoring of therapy response in immune checkpoint blockade and other therapies as well. This Research Topic focuses on the clinical application of neoantigens and how we can use them to guide our daily practice, modify canonical therapies, and develop novel strategies for cancer therapy. We will also discuss the challenges in the clinical application of neoantigens.
This Research Topic welcomes the submission of Original Research, Reviews and Methods, on themes including, but not limited to:
● Methods to detect and monitor the dynamic changes of neoantigens in a clinical setting.
● Neoantigens as a tool to guide clinical decisions on tumor treatment.
● Methods for the development of neoantigen-specific therapy.
Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases that are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.
Keywords: Neoantigen, neoantigen specific therapy, clinical
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.