About this Research Topic
Thoracic malignancies, including lung cancer, esophageal cancer, breast cancer, and more, are one of the major global health problems. Non-coding RNAs (ncRNAs), emerging as important regulators in various physiological conditions and pathological processes, have also been reported as such in thoracic malignancies. They play a critical role in carcinogenesis and progression, tumor immunology, as well as drug sensitivity/resistance of cancer cells. The genomic alterations and expression profiles of ncRNA genes are characteristics of thoracic cancers. Accumulating evidence suggests that the aberrantly expressed ncRNAs are potential prognostic/diagnostic biomarkers and therapeutic targets.
This Research Topic aims at promoting the understanding of ncRNAs in thoracic malignancies and providing new insights into their translational application. We welcome Original Research articles, Methods, Reviews, Mini Reviews, Perspectives and Opinions on the sub-themes below:
- Non-coding RNAs as diagnostic biomarkers for pathologic and histologic classification approaches
- Application of high-throughput data to detect ncRNAs as novel diagnostic and prognostic biomarkers
- Characterization of competitive endogenous RNA network to reveal the role of ncRNAs in thoracic cancers
- Non-coding RNAs as prognostic biomarkers for drug sensitivity/resistance, and metastasis
- Immunology and immunotherapy-related diagnostic and prognostic ncRNAs
Submissions not in scope for this specialty include:
Those consisting solely of bioinformatic investigation of publicly available genomic / transcriptomic data without experimental or in situ validation to support conclusions.
This Research Topic aims at promoting the understanding of ncRNAs in thoracic malignancies and providing new insights into their translational application. We welcome Original Research articles, Methods, Reviews, Mini Reviews, Perspectives and Opinions on the sub-themes below:
- Non-coding RNAs as diagnostic biomarkers for pathologic and histologic classification approaches
- Application of high-throughput data to detect ncRNAs as novel diagnostic and prognostic biomarkers
- Characterization of competitive endogenous RNA network to reveal the role of ncRNAs in thoracic cancers
- Non-coding RNAs as prognostic biomarkers for drug sensitivity/resistance, and metastasis
- Immunology and immunotherapy-related diagnostic and prognostic ncRNAs
Submissions not in scope for this specialty include:
Those consisting solely of bioinformatic investigation of publicly available genomic / transcriptomic data without experimental or in situ validation to support conclusions.
Keywords: Non-coding RNA, biomarker, thoracic malignancy
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
