About this Research Topic
Over the last decade, human microbiome research has been under the spotlight with a plethora of studies showing associations between specific microbiome profiles and health status. These studies very often report the contributing role of different bacterial groups in the development and prevention of a wide variety of diet-related diseases. Consequently, the characterization and use of probiotics strains, as well as prebiotic compounds, have been explored as an attractive approach to the prevention of such diseases.
Massive and parallel sequencing of the human gut microbiome has disclosed a great variety of microorganisms with potentially health-promoting effects. Moreover, different clinical trials show evidence that these potentially beneficial microbes can be modulated by individual dietary components. This Research Topic aims to highlight recent advances in this host-diet-microbe cross-talk in the context of human health. We intend to bring to light novel research focused on the remodeling of gut microbiota through diet towards understanding the molecular circuits underlying the microbiota-mediated health benefits of food supplements including probiotics, prebiotics, and synbiotics.
Articles on microbiome-driven effects of innovative functional foods on human health are of particular interest. Authors are encouraged to submit the cell host response evaluation and microbiota assessments of in vitro, pre-clinical or clinical trials accompanied by targeted or non-targeted (meta)metabolomics, (meta)transcriptomics, and (meta)proteomics approaches in an integrative manner. Microbiota functional assessments based exclusively on predictions using 16S rRNA gene amplicon sequencing data are discouraged. Functional metagenomics research based on experimental fosmid/bacmid/cosmid evaluation will be also considered.
We welcome submissions of Original Research, Review, Perspective, and Opinion articles.
Massive and parallel sequencing of the human gut microbiome has disclosed a great variety of microorganisms with potentially health-promoting effects. Moreover, different clinical trials show evidence that these potentially beneficial microbes can be modulated by individual dietary components. This Research Topic aims to highlight recent advances in this host-diet-microbe cross-talk in the context of human health. We intend to bring to light novel research focused on the remodeling of gut microbiota through diet towards understanding the molecular circuits underlying the microbiota-mediated health benefits of food supplements including probiotics, prebiotics, and synbiotics.
Articles on microbiome-driven effects of innovative functional foods on human health are of particular interest. Authors are encouraged to submit the cell host response evaluation and microbiota assessments of in vitro, pre-clinical or clinical trials accompanied by targeted or non-targeted (meta)metabolomics, (meta)transcriptomics, and (meta)proteomics approaches in an integrative manner. Microbiota functional assessments based exclusively on predictions using 16S rRNA gene amplicon sequencing data are discouraged. Functional metagenomics research based on experimental fosmid/bacmid/cosmid evaluation will be also considered.
We welcome submissions of Original Research, Review, Perspective, and Opinion articles.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
