About this Research Topic
This Research Topic focuses on cell crosstalk in DKD, including glomerular cells, tubular cells and resident or infiltrated immunocytes, with a particular interest on signal communications, redox, cellular targets that mediate proteinuria, glomerular sclerosis and interstitial fibrosis of DKD. We welcome submissions of Original Research and Reviews on the subtopics below, with function validation of in vitro or in vivo methods:
● Glomerular endothelial cell cross talk with podocytes in DKD
● Novel cell types identified by single cell RNA-seq in the development of DKD
● Immunocyte crosstalk with tubular epithelial cell or mesangial cells in the inflammation, interstitial fibrosis or glomerular sclerosis of DKD
● Crosstalk between tubular epithelial cells and glomerular endothelial cells in DKD
Keywords: Diabetic Kidney Disease, Single cell RNA sequencing, Cell Cross-talk, Podocyte Apoptosis, Endothelial Injury
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.