About this Research Topic
As we know, the perioperative period puts the patient under significant stress. Serious physiological changes take place that can be ameliorated or prevented in order to improve the treatment outcome.
The patients receive numerous drugs including general and regional anesthetics, opioids, antibiotics, sympathomimetic agents, muscle relaxants, imaging agents and other drugs, which increases the risks for adverse reactions and unpredicted interactions. This is especially actual for critically ill patients undergoing surgery.
Older patients and patients with morbid obesity, as well as those receiving chronic therapy (anticoagulants, opioids, etc.) comprise the other groups of increased risk due to reduced physiological functionality.
Thus, there are numerous questions and challenges regarding effective and safe perioperative drug management requiring further clarification. Among those are perioperative cardiovascular stability and prevention of perioperative cardiac death, postoperative pain control, effective prevention of postoperative nausea and vomiting (PONV), postsurgical ileus, anticoagulant and anti-platelet therapy, surgical versus conservative management of thrombotic complications in various surgical groups, postoperative cognitive disorders, and many others.
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All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Keywords: Perioperative Medicine, Intraoperative Pharmacotherapy, Anesthesia, Surgery, Intensive Care
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.