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ORIGINAL RESEARCH article

Front. Sustain. Food Syst.
Sec. Nutrition and Sustainable Diets
Volume 8 - 2024 | doi: 10.3389/fsufs.2024.1525572
This article is part of the Research Topic Bioactive Compounds from Medicinal Mushrooms and Plants - Extraction and Potential Application in Foods View all 6 articles

A Comprehensive Analysis on the Nutritional, Phytochemical, Antioxidant, Molecular docking and Toxicological Properties of Abies marocana Trab. Woody Biomass

Provisionally accepted
Malak ZIRARI Malak ZIRARI 1*Marouane AOUJI Marouane AOUJI 1WISSAL BAGHDAD WISSAL BAGHDAD 1Mohammed Er-rajy Mohammed Er-rajy 2Hamada Imtara Hamada Imtara 3*Feras Abujaber Feras Abujaber 3Otmane Elharrati Otmane Elharrati 1Omar M. Noman Omar M. Noman 4Mahmoud Tarayrah Mahmoud Tarayrah 5Driss Hmouni Driss Hmouni 1Nouredine El Mejdoub Nouredine El Mejdoub 1
  • 1 Ibn Tofail University, Kénitra, Rabat-Sale-Kenitra, Morocco
  • 2 Sidi Mohamed Ben Abdellah University, Fes, Morocco
  • 3 Arab American University, Jenin, Palestine
  • 4 King Saud University, Riyadh, Riyadh, Saudi Arabia
  • 5 National Center for Research in Human Genomics, Evry Courcouronnes, France

The final, formatted version of the article will be published soon.

    Morocco is renowned for its rich plant biodiversity, although many plants are underutilized. Consequently, the present study was conducted to assess the nutritional composition, bioactive constituents, antioxidant properties, and acute oral toxicity of Abies marocana's woody biomass. The nutritional value of the twigs and cones was determined using the AOAC method, while mineral components were examined through ICP-OES. To search for phytochemicals in the methanolic extracts, a number of established techniques were applied, and evaluate their antioxidant activity, while the volatile content was determined using the GC-MS method. The acute oral toxicity test was carried out following the guidelines of OECD 423. Proximate analysis revealed a variety of components in different parts, including moisture, ash, fiber, protein, carbohydrates, and fat. Cones and twigs were found to be rich in mineral elements, as well as phenols, flavonoids, tannins, and phytosterols. Chromatographic analysis identified linoleic acid as the main component in twig extract and 2-Bornanone as the primary constituent in cone extract. The methanolic extracts of A. marocana displayed strong antioxidant properties through notable DPPH scavenging activity, with no mortality observed in rats even at doses exceeding 1000 mg.kg -1 , indicating potential for medicinal, cosmetic, or dietary uses. A molecular docking study of the five main compounds of both plants showed that they aligned and interacted with the binding sites of selected proteins, demonstrating significant antioxidant activity.

    Keywords: Abies marocana, Nutritional value, Woody biomass, antioxidant activity, Acute oral toxicity, molecular docking

    Received: 09 Nov 2024; Accepted: 26 Dec 2024.

    Copyright: © 2024 ZIRARI, AOUJI, BAGHDAD, Er-rajy, Imtara, Abujaber, Elharrati, Noman, Tarayrah, Hmouni and Mejdoub. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Malak ZIRARI, Ibn Tofail University, Kénitra, 14000, Rabat-Sale-Kenitra, Morocco
    Hamada Imtara, Arab American University, Jenin, Palestine

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.