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MINI REVIEW article

Front. Nutr.

Sec. Clinical Nutrition

Volume 12 - 2025 | doi: 10.3389/fnut.2025.1539578

This article is part of the Research Topic Impact of Oxidation on Nutrition: Source, Absorption and Health Effects View all 4 articles

Diet, Oxidative Stress and MAFLD: a Mini Review

Provisionally accepted
  • 1 First Hospital of Lanzhou University, Lanzhou, Gansu Province, China
  • 2 Lanzhou University, Lanzhou, China
  • 3 The University of Sydney, Darlington, New South Wales, Australia

The final, formatted version of the article will be published soon.

    Globally, metabolic dysfunction-associated fatty liver disease (MAFLD), also known as non-alcoholic fatty liver disease (NAFLD) or metabolic dysfunction-associated steatotic liver disease (MASLD), is a common chronic liver disease. The progression of MAFLD leads to a vicious cycle in which oxidative stress results from the disease that is augmenting de-novo lipid levels and increases steatosis. Most non-enzymatic antioxidants are present in food. Therefore, the present review summarizes the findings of studies on food-derived antioxidants and presents an oxidative stress-related regulatory network in MAFLD, offering new ideas for MAFLD prevention and treatment.

    Keywords: Diet, Oxidative Stress, MAFLD, NAFLD, MASLD

    Received: 04 Dec 2024; Accepted: 18 Feb 2025.

    Copyright: © 2025 Hu, Yue, Jiang and Qiao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Liang Qiao, The University of Sydney, Darlington, NSW 2006, New South Wales, Australia

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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