The final, formatted version of the article will be published soon.
ORIGINAL RESEARCH article
Front. Microbiol.
Sec. Virology
Volume 16 - 2025 |
doi: 10.3389/fmicb.2025.1553129
Global burden and trends of viral hepatitis among women of childbearing age from 1990 to 2021
Provisionally accepted- 1 Jiangmen Maternity and Child Health Care Hospital, Jiangmen, China
- 2 Jiangmen Municipal Health Bureau, Jiangmen, China
Background: The burden and trends of viral hepatitis in women of childbearing age (WCBA) are rarely quantified. This study aimed to assess the global, regional, and national incidence and prevalence rates among WCBA from 1990 to 2021.Methods: From 1990 to 2021, We retrieved data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 on the incidence and prevalence of hepatitis A, B, C, and E for WCBA. Estimated annual percent change in the age-standardized incidence and prevalence rates were calculated to quantify the temporal trend. Results: In 2021, it was estimated that there were 42,266,708 new cases and 109,107,759 prevalent cases of viral hepatitis among WCBA globally. AHA had the highest incidence rate, while CHB had the highest prevalence rate globally. Notably, AHA and AHE were emerging in low-endemic regions. Generally, the burden of viral hepatitis decreased with higher SDI levels, except for AHA. Between 1990 and 2021, the global age-standardized incidence rate for viral hepatitis among WCBA decreased annually by -1.11% for acute hepatitis A (AHA), -1.24% for AHB, and -0.18% for AHC, -0.34% for AHE, with more significant reductions observed for chronic hepatitis B (CHB) and CHC at -1.33% and -0.29%, respectively. Furthermore, the burden of viral hepatitis continued to rise in lower-SDI regions, and the proportion of younger individuals affected increased as SDI decreased.Conclusions: Although the incidence and prevalence rates of viral hepatitis have decreased in recent decades, notable regional and demographic disparities remain. These concerning trends are especially pronounced in low-SDI regions, making it essential to tackle the disparities in healthcare resource allocation for WCBA across areas with varying SDI levels.
Keywords: Global burden of disease, Viral Hepatitis, Women of childbearing age, agestandardized rate, estimated annual percentage change
Received: 30 Dec 2024; Accepted: 05 Feb 2025.
Copyright: © 2025 Yang, Zhong, Huang, Lin and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Lu Huang, Jiangmen Maternity and Child Health Care Hospital, Jiangmen, China
Shengyuan Lin, Jiangmen Maternity and Child Health Care Hospital, Jiangmen, China
Yubin Li, Jiangmen Municipal Health Bureau, Jiangmen, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.