About this Research Topic

Background

Current biomedical knowledge has made it possible to demonstrate how the product of the neuron and brain structures represented by thought is subject to a series of changes in a pathological sense as the condition of the neuroanatomical structures and their functioning changes. Increasing evidence has pointed to the implication of inflammation in schizophrenia, and patients with diagnoses afferent to its spectrum have increased pro-inflammatory markers, multiple types of biomarkers, and a higher prevalence of inflammatory diseases. Furthermore, genetic and epigenetic studies have highlighted the role of the immune and endocrinological systems in schizophrenia, and some clinical trials have detected antipsychotic effects of anti-inflammatory drugs.

This Research Topic aims to examine, evaluate, or discuss the different molecular, biological, genetics, and neuroimaging aspects due to the consequences of the inflammation to identify risk factors, predictors, and possible protective factors or specific treatment methods.

Contributors are welcome to use the formats of an original research article, brief research report, systematic review, review, mini-review, policy and practice review, hypothesis and theory, perspective, case report, community case study, general commentary, or opinion. Studies addressing the following themes are strongly encouraged:

• Molecular aspects and changes in psychiatric disorders after inflammation

• Genetic and epigenetic aspects and changes of psychiatric pathologies resulting from inflammation

• Neuroimaging aspects and changes of psychiatric pathologies

• Neuroimmunology and neuroendocrinology in the patient with mental pathology

• BDNF and other biomarkers in the patient with brain inflammation

• Gut Microbiota and Covid-19. What interactions?

• Research of biomarkers related to psychiatric pathologies and neuroinflammation

• Research and proposal of a possible gold standard in the treatment of psychiatric pathology in case of neural inflammation

Keywords: Inflammation, Biomarkers, Neurobiology, Neuroimaging, Psychiatric genetics

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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