About this Research Topic
Nowadays, kidney diseases are one of the most important global health challenges that impose critical costs on citizens and governments. Over the past decades, extensive studies have been done on the causes of kidney diseases, including acute and chronic kidney diseases. However, there are still many ambiguous issues regarding the etiology, diagnosis, prevention, and treatment of these diseases. Furthermore, vitamins and minerals such as zinc, manganese, iron, and so on, play an important role in the physiology of various organs of the body including the kidneys, whereas the deficiency or excessive consumption of these micronutrients may cause injuries or enhance pathological conditions in the body. Past studies have shown some of the effects of different vitamins and minerals on renal and urinary tract function, however, there are still many questions yet to be answered. With this Research Topic, we aim to discuss the current understanding on the role of micronutrients in renal physiology and pathophysiology. We hope to gather relevant data to highlight the relevance of this subject.
The main issues that we intend to address in this Research Topic with the proposed studies are the following:
• What is the role of the different vitamins and minerals in the normal function of the kidneys?
• What is the underlying molecular mechanism of micronutrients in renal physiology and physiopathology of kidney diseases?
• What are the new prevention, diagnosis, and therapeutic/treatment strategies for kidney diseases based on micronutrients?
Given these main objectives, this Research Topic aims to:
• investigate the relationship between diseases affecting the absorption and metabolism of micronutrients and the incidence and prevalence of kidney disease
• provide an understanding of the role of vitamins and their metabolites in renal biochemical and molecular pathways
• explore the protective or potentially harmful role of various micronutrients in the prevention of acute and chronic kidney disease with emphasis on oxidative stress, apoptosis, necrosis, inflammation, and other important molecular pathways
• study the role of micronutrients in reducing or increasing the renal physiological response to environmental pollutants, hazardous materials, chemicals, radiation, and other harmful substances
• determine the association of different micronutrients with complications of renal dialysis and transplantation
• explore the role of micronutrients in kidney disease affecting the other body systems such as the immune, cardiovascular, skeletal, nervous, and reproductive systems.
The main issues that we intend to address in this Research Topic with the proposed studies are the following:
• What is the role of the different vitamins and minerals in the normal function of the kidneys?
• What is the underlying molecular mechanism of micronutrients in renal physiology and physiopathology of kidney diseases?
• What are the new prevention, diagnosis, and therapeutic/treatment strategies for kidney diseases based on micronutrients?
Given these main objectives, this Research Topic aims to:
• investigate the relationship between diseases affecting the absorption and metabolism of micronutrients and the incidence and prevalence of kidney disease
• provide an understanding of the role of vitamins and their metabolites in renal biochemical and molecular pathways
• explore the protective or potentially harmful role of various micronutrients in the prevention of acute and chronic kidney disease with emphasis on oxidative stress, apoptosis, necrosis, inflammation, and other important molecular pathways
• study the role of micronutrients in reducing or increasing the renal physiological response to environmental pollutants, hazardous materials, chemicals, radiation, and other harmful substances
• determine the association of different micronutrients with complications of renal dialysis and transplantation
• explore the role of micronutrients in kidney disease affecting the other body systems such as the immune, cardiovascular, skeletal, nervous, and reproductive systems.
Keywords: Micronutrients, Renal Physiology, Renal Pathophysiology, Kidney Diseases, Vitamins, Minerals
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
