Green perspective of nano-biotechnology: Nanotoxicity horizon to biomedical applications

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About this Research Topic

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Background

The recent decade has seen a multidimensional advancement of nanotechnologies towards environmental and biomedical applications. However, such increasing employment in different fields has also raised concerns about safety issues related to the environment and human health. A green and sustainable production of nanomaterial has the potential of providing the solution. However, this approach needs more advancement, refinement, and a detailed study of nanomaterials comparative toxicity. To explore the applicability of green fabricated nanomaterials, it is important to assess their cellular and molecular toxicity using different in vitro and in vivo models. These include the mode of nanomaterials internalization and accumulation, cellular and molecular interactions with different biomolecules, genotoxicity, and their consequent effect. These different aspects need to be fully understood in order to fabricate nanomaterials with desired properties and reduced toxicity.

This research topic is intended to explore the green and sustainable approaches taken for nanobiotechnology applications, with particular emphasis on the detailed studies of mechanistic nanotoxicology. Hence, we aim to present the latest advances in green fabrication of nanomaterials and exploring their potential nano-biocompatibility for different biomedical and environmental applications. In quest of applicability of the green synthesized nanomaterials, this research topic aims to excavate the mechanism of biomedical and environmental toxicity of nanomaterials, with a special focus on metallic nanoparticles, their composites, and possible ways to reduce their toxicity through a green approach.

The research topic invites papers on, but not limited to, the following topics:
• Biomedical and ecological toxicity of nanomaterials.
• Molecular and mechanistic description of nanomaterials toxicology.
• Comparative and lifecycle assessment of green synthesized nanomaterials toxicity.
• Metallic nanoparticles and their composite risk assessment.
• Green synthesis and sustainable applications of nanomaterials.

Keywords: Green nanotechnology, Nanotoxicity, in vitro toxicity, in vivo toxicity

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