About this Research Topic
The reconstruction of the neural network is the ultimate purpose of the treatment for brain injury, such as stroke, trauma, cerebral palsy, neurodegenerative disorder, et al. The plasticity in brain injury is different from regeneration of the spinal cord in spinal cord injury: it occurs in a complex environment that includes neural stem cells, injured neurons (surviving bodies and dead axons or synapses), denervated intact neurons and glia, et al. The regenerative process includes endogenous neurogenesis, axon regeneration, myelination, and synaptogenesis. This Research Topic is devoted to the cellular and molecular mechanisms of plasticity in brain injury, and to meaningful exploration for the promotion of neural plasticity following brain injury.
Surrounding this Research Topic “Plasticity and Reconstruction of Neural Networks in Brain Injury”, we will welcome high-quality contributions from excellent neuroscientists worldwide on basic research and clinical studies. These manuscripts can be original research articles, minireviews, reviews, comments, meta-analyses, case report and can cover the following areas:
- The detection method of brain plasticity, such as imaging and tracer technique,
- Cellular and molecular mechanisms,
- Factors involved in the neural plasticity,
- Interventional strategies promoting this process.
Keywords: stroke, trauma, plasticity, reconstruction of neural network, synaptogenesis
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.