Molecular Strategies Aimed to Boost NK Cell-based Immunotherapy of Cancer

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ORIGINAL RESEARCH

Published on 03 Dec 2019

The Synergistic Use of IL-15 and IL-21 for the Generation of NK Cells From CD3/CD19-Depleted Grafts Improves Their ex vivo Expansion and Cytotoxic Potential Against Neuroblastoma: Perspective for Optimized Immunotherapy Post Haploidentical Stem Cell Transplantation

  • Annekathrin Heinze
  • Beatrice Grebe
  • Melanie Bremm
  • Sabine Huenecke
  • Tasleem Ah. Munir
  • Lea Graafen
  • Jochen T. Frueh
  • Michael Merker
  • Eva Rettinger
  • 4 more
  • Claudia Cappel
The Synergistic Use of IL-15 and IL-21 for the Generation of NK Cells From CD3/CD19-Depleted Grafts Improves Their ex vivo Expansion and Cytotoxic Potential Against Neuroblastoma: Perspective for Optimized Immunotherapy Post Haploidentical Stem Cell Transplantation
doi 10.3389/fimmu.2019.02816
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  • 48 citations

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