About this Research Topic
The crucial aims of this research topic are to investigate not only the recent advances but also identify the gaps in the fields of developmental biology, cancer etiology, and Hh inhibitors, using mammals, mouse and fly as models. We also welcome the authors to contribute to this Research topic by submitting either original studies or review articles. We also encourage the submission of studies that combine several disciplines and tools such as Hedgehog and development, genetics and cancer, aberrant hedgehog pathway in cancer, Hh signaling and its mutation in cancer and development.
Submission of research papers on the following topics will be highly appreciated:
• Role of aberrant GLI signaling in ovarian and gynecological cancer
• Role of HH/GLI pathway in cancer stemness
• Updates of HH/GLI pathway inhibitors for treatment of cancer
• Role of HH/GLI pathway in Pancreatic and Colon cancer
• Role of aberrant GLI signaling in Breast and hematological cancer
Keywords: Hh signaling, GLIs, Cilia, Development, Cancer, PTCH, Morphogens
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.