Fluxomics and Metabolic Flux Analysis in Systems Microbiology

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ORIGINAL RESEARCH

Published on 25 Jun 2019

Membrane-Inlet Mass Spectrometry Enables a Quantitative Understanding of Inorganic Carbon Uptake Flux and Carbon Concentrating Mechanisms in Metabolically Engineered Cyanobacteria

Damien Douchi
Feiyan Liang
Melissa Cano
Wei Xiong
Bo Wang
Pin-Ching Maness
Peter Lindblad
Jianping Yu

doi 10.3389/fmicb.2019.01356

3,788 views
25 citations

TECHNOLOGY REPORT

Published on 24 May 2019

The Design of FluxML: A Universal Modeling Language for 13C Metabolic Flux Analysis

Martin Beyß
Salah Azzouzi
Michael Weitzel
Wolfgang Wiechert
Katharina Nöh

doi 10.3389/fmicb.2019.01022

6,666 views
29 citations

ORIGINAL RESEARCH

Published on 07 May 2019

13C-Metabolic Flux Analysis Reveals Effect of Phenol on Central Carbon Metabolism in Escherichia coli

Sayaka Kitamura
Yoshihiro Toya
Hiroshi Shimizu

doi 10.3389/fmicb.2019.01010

4,317 views
15 citations

METHODS

Published on 30 Apr 2019

EMUlator: An Elementary Metabolite Unit (EMU) Based Isotope Simulator Enabled by Adjacency Matrix

Chao Wu
Chia-hsin Chen
Jonathan Lo
William Michener
PinChing Maness
Wei Xiong

doi 10.3389/fmicb.2019.00922

2,943 views
5 citations

ORIGINAL RESEARCH

Published on 17 Apr 2019

Dietary Energy Level Promotes Rumen Microbial Protein Synthesis by Improving the Energy Productivity of the Ruminal Microbiome

Zhongyan Lu
Zhihui Xu
Zanming Shen
Yuanchun Tian
Hong Shen

doi 10.3389/fmicb.2019.00847

12,919 views
66 citations

MINI REVIEW

Published on 05 Apr 2019

Approaches to Computational Strain Design in the Multiomics Era

Peter C. St. John
Yannick J. Bomble

doi 10.3389/fmicb.2019.00597

5,140 views
22 citations

ORIGINAL RESEARCH

Published on 01 Feb 2019

13C-Metabolic Flux Analysis Reveals the Metabolic Flux Redistribution for Enhanced Production of Poly-γ-Glutamic Acid in dlt Over-Expressed Bacillus licheniformis

Penghui He
Ni Wan
Dongbo Cai
Shiying Hu
Yaozhong Chen
Shunyi Li
Shouwen Chen

doi 10.3389/fmicb.2019.00105

3,147 views
17 citations

METHODS

Published on 24 Jan 2019

Tandem Mass Spectrometry for 13C Metabolic Flux Analysis: Methods and Algorithms Based on EMU Framework

Jungik Choi
Maciek R. Antoniewicz

doi 10.3389/fmicb.2019.00031

3,879 views
21 citations

ORIGINAL RESEARCH

Published on 21 Nov 2018

Flux Connections Between Gluconate Pathway, Glycolysis, and Pentose–Phosphate Pathway During Carbohydrate Metabolism in Bacillus megaterium QM B1551

Julie A. Wushensky
Tracy Youngster
Caroll M. Mendonca
Ludmilla Aristilde

doi 10.3389/fmicb.2018.02789

8,657 views
32 citations

ORIGINAL RESEARCH

Published on 20 Nov 2018

Bacterial Metabolism During Biofilm Growth Investigated by 13C Tracing

Ni Wan
Hao Wang
Chun Kiat Ng
Manisha Mukherjee
Dacheng Ren
Bin Cao
Yinjie J. Tang

doi 10.3389/fmicb.2018.02657

9,716 views
49 citations

ORIGINAL RESEARCH

Published on 23 Aug 2018

Isotope-Assisted Metabolite Analysis Sheds Light on Central Carbon Metabolism of a Model Cellulolytic Bacterium Clostridium thermocellum

Wei Xiong
Jonathan Lo
Katherine J. Chou
Chao Wu
Lauren Magnusson
Tao Dong
PinChing Maness

doi 10.3389/fmicb.2018.01947

3,048 views
20 citations

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Microbial Physiology and Metabolism
Systems Microbiology

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Articles

Membrane-Inlet Mass Spectrometry Enables a Quantitative Understanding of Inorganic Carbon Uptake Flux and Carbon Concentrating Mechanisms in Metabolically Engineered Cyanobacteria

The Design of FluxML: A Universal Modeling Language for 13C Metabolic Flux Analysis

13C-Metabolic Flux Analysis Reveals Effect of Phenol on Central Carbon Metabolism in Escherichia coli

EMUlator: An Elementary Metabolite Unit (EMU) Based Isotope Simulator Enabled by Adjacency Matrix

Dietary Energy Level Promotes Rumen Microbial Protein Synthesis by Improving the Energy Productivity of the Ruminal Microbiome

Approaches to Computational Strain Design in the Multiomics Era

13C-Metabolic Flux Analysis Reveals the Metabolic Flux Redistribution for Enhanced Production of Poly-γ-Glutamic Acid in dlt Over-Expressed Bacillus licheniformis

Tandem Mass Spectrometry for 13C Metabolic Flux Analysis: Methods and Algorithms Based on EMU Framework

Flux Connections Between Gluconate Pathway, Glycolysis, and Pentose–Phosphate Pathway During Carbohydrate Metabolism in Bacillus megaterium QM B1551

Bacterial Metabolism During Biofilm Growth Investigated by 13C Tracing

Isotope-Assisted Metabolite Analysis Sheds Light on Central Carbon Metabolism of a Model Cellulolytic Bacterium Clostridium thermocellum

Frontiers in Microbiology

Microbial Physiology and Metabolism

Systems Microbiology