EDITORIAL
Published on 18 Feb 2019
Editorial: Multi-Target-Directed Ligands (MTDL) as Challenging Research Tools in Drug Discovery: From Design to Pharmacological Evaluation
doi 10.3389/fchem.2019.00071
- 4,369 views
- 40 citations
- Frontiers in Chemistry
- Medicinal and Pharmaceutical Chemistry
- Research Topics
- Multi-target-directed ligands (MTDL) as challenging research tools in drug discovery: from design to pharmacological evaluation
Multi-target-directed ligands (MTDL) as challenging research tools in drug discovery: from design to pharmacological evaluation
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Articles
ORIGINAL RESEARCH
Published on 24 Jul 2018
Common G-Quadruplex Binding Agents Found to Interact With i-Motif-Forming DNA: Unexpected Multi-Target-Directed Compounds
doi 10.3389/fchem.2018.00281
- 8,198 views
- 75 citations
ORIGINAL RESEARCH
Published on 03 Jul 2018
Selenazolyl-hydrazones as Novel Selective MAO Inhibitors With Antiproliferative and Antioxidant Activities: Experimental and In-silico Studies
doi 10.3389/fchem.2018.00247
- 4,632 views
- 41 citations
ORIGINAL RESEARCH
Published on 26 Jun 2018
Probing Substituents in the 1- and 3-Position: Tetrahydropyrazino-Annelated Water-Soluble Xanthine Derivatives as Multi-Target Drugs With Potent Adenosine Receptor Antagonistic Activity
doi 10.3389/fchem.2018.00206
- 3,065 views
- 10 citations
ORIGINAL RESEARCH
Published on 28 May 2018
Evidence for a Cyanine Link Between Propargylamine Drugs and Monoamine Oxidase Clarifies the Inactivation Mechanism
doi 10.3389/fchem.2018.00169
- 2,624 views
- 25 citations
ORIGINAL RESEARCH
Published on 24 May 2018
Recovering Actives in Multi-Antitarget and Target Design of Analogs of the Myosin II Inhibitor Blebbistatin
doi 10.3389/fchem.2018.00179
- 2,211 views
- 1 citation
ORIGINAL RESEARCH
Published on 09 May 2018
Data Mining and Machine Learning Models for Predicting Drug Likeness and Their Disease or Organ Category
doi 10.3389/fchem.2018.00162
- 10,892 views
- 42 citations
ORIGINAL RESEARCH
Published on 23 Apr 2018
Hydroxybenzoic Acid Derivatives as Dual-Target Ligands: Mitochondriotropic Antioxidants and Cholinesterase Inhibitors
doi 10.3389/fchem.2018.00126
- 5,525 views
- 39 citations
TECHNOLOGY REPORT
Published on 19 Apr 2018
The Mu.Ta.Lig. Chemotheca: A Community-Populated Molecular Database for Multi-Target Ligands Identification and Compound-Repurposing
doi 10.3389/fchem.2018.00130
- 2,717 views
- 16 citations
