Nutraceutical Formulations and Natural Compounds for the Management of Chronic Diseases

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About this Research Topic

Submission deadlines

  1. Manuscript Summary Submission Deadline 4 March 2025 | Manuscript Submission Deadline 22 June 2025

  2. This Research Topic is still accepting articles.

Background

Chronic diseases, including cardiovascular diseases, type 2 diabetes, neurodegenerative disorders, and cancer, represent a significant global health burden, contributing to over 70% of deaths worldwide. These conditions often result from long-term risk factors, including poor diet, sedentary lifestyles, and environmental stressors, which contribute to systemic inflammation and oxidative damage. In recent years, there has been growing interest in the therapeutic potential of natural compounds and nutraceuticals for the management of chronic illnesses. Bioactive natural compounds such as polyphenols, carotenoids, terpenoids, and alkaloids, have demonstrated preventive effects by reducing oxidative damage, regulating inflammatory pathways, and maintaining metabolic balance. Unlike synthetic treatments, natural compounds offer a safer and more sustainable approach, aligning with the increasing demand for preventive healthcare strategies.

Venting disease progression and improving patient outcomes. To achieve this, we seek contributions that investigate the therapeutic efficacy of natural compounds, reporting their potential biological activity in in vitro/in vivo/ex vivo models and clinical trials. By promoting interdisciplinary research and emphasizing evidence-based approaches, this Special Issue aspires to provide a comprehensive understanding of the role of natural compounds in chronic disease prevention and management, ultimately paving the way for safer, more sustainable healthcare solutions.

This Research Topic focuses on the role of natural compounds in the prevention and management of chronic diseases, including cardiovascular disorders, diabetes, neurodegenerative conditions, and chronic inflammatory diseases. We welcome contributions that explore the therapeutic potential of bioactive natural compounds, emphasizing their mechanisms of action, clinical efficacy, and potential for integration into healthcare practices.
Specific themes include:
• Anti-inflammatory and antioxidant properties of natural compounds.
• The role of natural compounds in modulating metabolic pathways.
• Development of nutraceutical formulations targeting chronic diseases.
• Preclinical and clinical studies on the safety and efficacy of natural compounds.
• Case studies highlighting successful applications of natural compounds in disease management.
We encourage submissions of original research, reviews, clinical trials, meta analysis, and perspective articles.

This Research Topic aims to provide a comprehensive overview of the field, promoting interdisciplinary collaboration and advancing knowledge on sustainable and innovative approaches to chronic disease management.

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This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

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  • Hypothesis and Theory
  • Methods

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Keywords: Chronic diseases, Natural compounds, Oxidative stress, Metabolic syndrome

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