About this Research Topic
In cellular biology, hormones are fundamental to signaling processes that influence cellular behavior, impacting various physiological states including inflammation and cancer progression. Hormonal interactions, such as those mediated by insulin, estrogen, testosterone, and thyroid hormones, play complex roles in these processes. Testosterone, noted for its anti-inflammatory properties, interacts through diverse pathways, while thyroid hormones modulate inflammation via nuclear receptors. Growth hormone's involvement in cancers like prostate cancer highlights its potential as both a growth factor and a therapeutic target.
In recent years, hormone therapy (endocrine therapy) has become one of the standard treatment options for certain types of cancer, such as breast, prostate, and thyroid cancer. Hormone replacement therapy and hormone antagonists can improve patient prognosis by modulating hormone levels while alleviating inflammatory responses. Additionally, researchers are exploring the potential of small molecule hormone antagonists and targeted hormone signaling pathways to develop more precise therapeutic approaches. These new findings offer fresh perspectives that could significantly enhance treatment outcomes for patients with inflammation and cancer in future clinical applications.
This Research Topic aims to compile the latest research findings to investigate the roles of hormones in these pathological states, particularly focusing on inflammation and cancer, and to propose new therapeutic strategies based on these insights.
We welcome submissions from researchers in all fields, especially in the following directions:
o Hormonal influence on signaling pathways and their roles in inflammation and cancer
o Hormonal regulation of immune responses in chronic inflammatory diseases
o Application of hormone replacement therapy in cancer treatment and its effects on inflammation
o Advanced research on novel small molecule hormone antagonists and their potential in targeted cancer therapy
o Associations between hormones and metabolic syndromes in inflammation and cancer progression
o Hormonal dynamics within the tumor microenvironment
o Comprehensive risk/benefit analyses of hormone therapies
o Integrative approaches combining epigenetics and epidemiology for early cancer diagnosis and therapeutic target search
o Machine and deep learning approaches to identify new hormonal targets and their antagonists
o Bioinformatic analysis of hormone-related gene expression and its impact on inflammation and cancer prognosis.
In recent years, hormone therapy (endocrine therapy) has become one of the standard treatment options for certain types of cancer, such as breast, prostate, and thyroid cancer. Hormone replacement therapy and hormone antagonists can improve patient prognosis by modulating hormone levels while alleviating inflammatory responses. Additionally, researchers are exploring the potential of small molecule hormone antagonists and targeted hormone signaling pathways to develop more precise therapeutic approaches. These new findings offer fresh perspectives that could significantly enhance treatment outcomes for patients with inflammation and cancer in future clinical applications.
This Research Topic aims to compile the latest research findings to investigate the roles of hormones in these pathological states, particularly focusing on inflammation and cancer, and to propose new therapeutic strategies based on these insights.
We welcome submissions from researchers in all fields, especially in the following directions:
o Hormonal influence on signaling pathways and their roles in inflammation and cancer
o Hormonal regulation of immune responses in chronic inflammatory diseases
o Application of hormone replacement therapy in cancer treatment and its effects on inflammation
o Advanced research on novel small molecule hormone antagonists and their potential in targeted cancer therapy
o Associations between hormones and metabolic syndromes in inflammation and cancer progression
o Hormonal dynamics within the tumor microenvironment
o Comprehensive risk/benefit analyses of hormone therapies
o Integrative approaches combining epigenetics and epidemiology for early cancer diagnosis and therapeutic target search
o Machine and deep learning approaches to identify new hormonal targets and their antagonists
o Bioinformatic analysis of hormone-related gene expression and its impact on inflammation and cancer prognosis.
Keywords: Hormonal interaction, Inflammation, Cancer progression
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
