Cancer pain is a multifaceted and often debilitating symptom that significantly impairs the quality of life of patients. Despite advancements in pain management techniques, achieving optimal pain control remains challenging due to the complex nature of cancer pain and the need for highly individualized treatment plans. Artificial Intelligence (AI) presents a promising frontier in this domain, offering novel solutions to enhance the accuracy, efficiency, and personalization of pain management strategies for cancer patients.

This Research Topic will explore the transformative potential of AI in addressing the various dimensions of cancer pain management. We aim to gather cutting-edge research that illuminates how AI technologies can be leveraged to improve pain assessment, prediction, monitoring, and therapeutic interventions, ultimately advancing patient care and outcomes.

Key themes include, but are not limited to:

1. AI-Driven Pain Assessment: Investigating AI methodological and clinical applications in objective pain assessment tools, such as wearable sensors, facial recognition software, and natural language processing to evaluate patient-reported outcomes and pain intensity.

2. Predictive Analytics for Pain Management: Utilizing machine learning models to predict pain trajectories, treatment responses, and potential side effects, enabling proactive and personalized pain management interventions.

3. Precision Medicine and AI: Examining how AI can help tailor pain management strategies based on genetic/ pharmacogenomics, molecular, and clinical data to enhance treatment efficacy) and reduce adverse effects.

4. AI in Pharmacological Pain Management: Exploring the use of AI to optimize drug selection, dosing regimens, and combination therapies for personalized cancer pain relief, including minimizing opioid dependency and adverse events.

5. Non-Pharmacological Interventions: Assessing and testing AI-enabled approaches to integrating complementary therapies such as psychological interventions, physical therapies, and neuromodulation techniques within comprehensive pain management plans.

6. Telemedicine and Remote Monitoring: Discussing AI applications that facilitate remote monitoring of cancer pain using telehealth platforms, mobile apps, and other digital health tools, ensuring continuous, real-time, and adaptive pain management.

7. Patient-Centered Care: Investigating how AI can enhance patient (and caregivers) engagement, education, and self-management in cancer pain, fostering a more holistic approach to patient care.

8. Data Integration and Interoperability: Addressing challenges and solutions related to integrating and harmonizing diverse longitudinal data sources (e.g., electronic health records, imaging, genomics) to create robust AI models for cancer pain management.

9. Ethical and Regulatory Considerations: Exploring ethical, privacy, social, and regulatory issues surrounding the development and use of AI in cancer pain management, ensuring safe, trustful, unbiased, and equitable patient care.

10. Clinical Trials and Implementation: Presenting studies on the implementation and governance of AI-driven pain management solutions in clinical settings, including pilot projects, simulations, clinical trials, and real-world applications.

11. AI Education in Cancer Pain Management: Given the rapid advancements in AI technology, it is essential to prioritize education and training for healthcare professionals and patients. The research topic will cover AI literacy and training programs for healthcare providers, Patient education initiatives on the benefits and limitations of AI-powered pain management tools and Ethical considerations related to AI education and patient privacy

We invite original research articles, comprehensive reviews, clinical trials, perspectives, and case studies that provide insights into these and related themes. Our goal is to foster a multidisciplinary dialogue that advances the use of AI in cancer pain management, ultimately aiming to improve patient outcomes and quality of life.

Join us in this important endeavor to explore the potential of AI to revolutionize cancer pain management, making strides toward more effective, personalized, and compassionate care.

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Frontiers in Pain Research

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