About this Research Topic
Clear cell renal cell carcinoma (ccRCC) is notably characterized by abnormal lipid and glucose metabolism, which not only perturbs the cellular energetics but also impacts the surrounding tumor microenvironment, influencing anti-tumor immunity. This abnormal metabolism is closely linked with perirenal fat invasion, tissue necrosis, immune infiltration, and, consequently, poorer survival rates in patients. Additionally, metabolic interventions by chemotherapy highlight the complexity of cancer treatment effects on both tumor biology and patient quality of life. These interconnections underscore the necessity for comprehensive research into the metabolic and immunological underpinnings of urological cancers.
This Research Topic aims to decipher the complex interplay between metabolism, immunology, and tumor metastasis in urological cancers. By utilizing advanced molecular marker screening, bioinformatics, molecular biology, and epidemiological methods, our objective is to unearth pivotal molecular mechanisms and biomarkers that drive abnormal metabolic and immunological conditions in urological cancers. The ultimate goal is to harness these insights for the development of more effective therapeutic strategies, potentially improving prognosis and treatment efficacy in urological oncology.
To advance understanding in this critical area, we invite submissions of Original Research, Reviews, Mini Reviews, and Perspectives focusing on a range of fundamental and translational aspects, including:
• Discovery of biomarkers and underlying mechanisms in metabolism and immunology of urological cancers.
• Investigation of molecular pathways influenced by metabolism and immunology within urological cancer scenarios.
• Examination of how metabolic and immunological processes impact tumor behavior and patient outcomes in urological cancers.
This Research Topic aims to decipher the complex interplay between metabolism, immunology, and tumor metastasis in urological cancers. By utilizing advanced molecular marker screening, bioinformatics, molecular biology, and epidemiological methods, our objective is to unearth pivotal molecular mechanisms and biomarkers that drive abnormal metabolic and immunological conditions in urological cancers. The ultimate goal is to harness these insights for the development of more effective therapeutic strategies, potentially improving prognosis and treatment efficacy in urological oncology.
To advance understanding in this critical area, we invite submissions of Original Research, Reviews, Mini Reviews, and Perspectives focusing on a range of fundamental and translational aspects, including:
• Discovery of biomarkers and underlying mechanisms in metabolism and immunology of urological cancers.
• Investigation of molecular pathways influenced by metabolism and immunology within urological cancer scenarios.
• Examination of how metabolic and immunological processes impact tumor behavior and patient outcomes in urological cancers.
Keywords: urology cancer, biomarkers, molecular mechanisms, immunology, therapeutic potential
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
