About this Research Topic
The field of immune biology, particularly in relation to infectious and inflammatory diseases, represents a rapidly progressing area of study. With continuous advancements in biomedical technologies like next-generation sequencing and multi-omics, researchers are gaining intricate insights into how the immune system confronts pathogens. These interactions, pivotal for determining health or disease outcomes, are increasingly revealed through cutting-edge tools that allow for a detailed exploration of immune responses at the cellular and molecular level. Noteworthy progress includes elaborating immune pathways in critical conditions such as COVID-19, tuberculosis, and various autoimmune diseases. This detailed insight is pivotal, facilitating the discovery of new therapeutic targets and boosting vaccine development and its efficacy.
This Research Topic aims to extend the current understanding of immune system behaviors and their implications for infectious and inflammatory diseases. The primary objective is to explore how distinct immune cell subsets contribute to disease pathogenesis and to assess the impact of genetic and environmental factors on these immune responses. Additionally, the goal encompasses the development of innovative models for studying host-pathogen dynamics to enhance therapeutic and preventive strategies.
To deepen our understanding within this expansive field, submissions are encouraged that cover, but are not limited to, the following themes:
- Investigation of specific immune cell roles in the pathogenesis of diseases.
- Analysis of the genetic and environmental determinants impacting immune system responses.
- Creation and validation of new model systems for the exploration of host-pathogen interactions.
- Studies addressing immune system dysregulation in chronic diseases like rheumatoid arthritis and inflammatory bowel disease.
- Contributions linking laboratory research to clinical practice through translational studies.
In bridging the gaps between laboratory findings and clinical practice, this call for manuscripts invites submissions of original research, comprehensive review articles, and detailed case studies. Emphasis is given to works that integrate systems biology with computational modelling and experimental research, thereby offering a holistic view of immune regulation and function.
The topic editors declare no conflicts of interest
This Research Topic aims to extend the current understanding of immune system behaviors and their implications for infectious and inflammatory diseases. The primary objective is to explore how distinct immune cell subsets contribute to disease pathogenesis and to assess the impact of genetic and environmental factors on these immune responses. Additionally, the goal encompasses the development of innovative models for studying host-pathogen dynamics to enhance therapeutic and preventive strategies.
To deepen our understanding within this expansive field, submissions are encouraged that cover, but are not limited to, the following themes:
- Investigation of specific immune cell roles in the pathogenesis of diseases.
- Analysis of the genetic and environmental determinants impacting immune system responses.
- Creation and validation of new model systems for the exploration of host-pathogen interactions.
- Studies addressing immune system dysregulation in chronic diseases like rheumatoid arthritis and inflammatory bowel disease.
- Contributions linking laboratory research to clinical practice through translational studies.
In bridging the gaps between laboratory findings and clinical practice, this call for manuscripts invites submissions of original research, comprehensive review articles, and detailed case studies. Emphasis is given to works that integrate systems biology with computational modelling and experimental research, thereby offering a holistic view of immune regulation and function.
The topic editors declare no conflicts of interest
Keywords: Immune responses, Infectious diseases, Inflammatory diseases, Pathogen interactions, Immune cell subsets, Vaccine development, Host-pathogen dynamics, Autoimmune disorders, Systems biology, Translational research
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
