ORIGINAL RESEARCH
Accepted on 14 Nov 2025
- Frontiers in Pharmacology
- Drug Metabolism and Transport
- Research Topics
- Integrated PK/PD and Drug Metabolism Approaches in Drug Development and Evaluation
Integrated PK/PD and Drug Metabolism Approaches in Drug Development and Evaluation
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Articles
CLINICAL TRIAL
Accepted on 10 Nov 2025
Clinical trial on the pharmacokinetics, pharmacodynamics and safety of tolvaptan in healthy Chinese males: an open-label, single and multiple dosage, parallel group study
- 128 views
CLINICAL TRIAL
Accepted on 20 Oct 2025
Population pharmacokinetics/pharmacodynamics and safety of YPEG-rhGH in elderly subjects
- 209 views
ORIGINAL RESEARCH
Published on 17 Oct 2025
QSAR-based physiologically based pharmacokinetic (PBPK) modeling for 34 fentanyl analogs: model validation, human pharmacokinetic prediction and abuse risk insights
doi 10.3389/fphar.2025.1692293
- 1,344 views
CLINICAL TRIAL
Published on 16 Oct 2025
Comparative study of the pharmacokinetics, efficacy and safety of ET-26 in elderly and non-elderly subjects: the results of a phase I clinical trial
doi 10.3389/fphar.2025.1665322
- 644 views
ORIGINAL RESEARCH
Published on 30 Sep 2025
Study on cerebrospinal fluid meropenem, vancomycin and tigecycline monitoring in patients with central nervous system infection following neurosurgery under different drug regimens
doi 10.3389/fphar.2025.1666168
- 1,834 views
ORIGINAL RESEARCH
Published on 09 Sep 2025
Synthesis, pharmacokinetic studies, and metabolite analysis of meridianin C in rats using a validated ultra high performance liquid chromatography-tandem mass spectrometry method
doi 10.3389/fphar.2025.1633157
- 914 views
ORIGINAL RESEARCH
Published on 19 Aug 2025
Population pharmacokinetics/pharmacodynamics analysis confirming biosimilarity of SB16 to reference denosumab
doi 10.3389/fphar.2025.1631034
- 1,454 views
ORIGINAL RESEARCH
Published on 29 Apr 2025
Effect of ABCB1 SNP polymorphisms on the plasma concentrations and clinical outcomes of rivaroxaban in Chinese NVAF patients: a population pharmacokinetic-based study
doi 10.3389/fphar.2025.1574949
- 1,880 views
- 1 citation
ORIGINAL RESEARCH
Published on 28 Apr 2025
Prediction of pharmacokinetic/pharmacodynamic properties of aldosterone synthase inhibitors at drug discovery stage using an artificial intelligence-physiologically based pharmacokinetic model
doi 10.3389/fphar.2025.1578117
- 3,484 views
- 3 citations
ORIGINAL RESEARCH
Published on 10 Apr 2025
A mechanistic quantitative systems pharmacology model platform for translational efficacy evaluation and checkpoint combination design of bispecific immuno-modulatory antibodies
doi 10.3389/fphar.2025.1571844
- 2,594 views
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