About this Research Topic
Alterations in gut microbiota composition and immune cell populations can lead to dysregulated immune responses, increasing the risk of transplant rejection or complications. This intricate interplay necessitates a comprehensive understanding of how gut health affects kidney transplantation, highlighting the potential for therapeutic interventions aimed at optimizing both gut and kidney function.
The interplay between the gut and kidney has garnered significant attention in recent years, particularly concerning its role in modulating the immune response in kidney transplant recipients. The gut is home to a complex ecosystem of microbiota and immune cells that contribute to systemic immunity and may influence transplant outcomes.
Understanding the gut-kidney axis is crucial for developing strategies to enhance graft survival and improve the overall health of kidney transplant recipients. This Research Topic aims to elucidate the mechanisms by which gut immune cells and microbiota affect the immune microenvironment in kidney transplant recipients. We seek to address critical questions regarding the relationship between gut health and transplant outcomes, including how alterations in gut microbiota may predispose recipients to acute rejection or chronic allograft dysfunction.
Additionally, we encourage investigations into potential therapeutic interventions targeting the gut microbiome or immune modulation strategies that could optimize immune responses and enhance transplant success. By assembling a collection of studies that highlight these interactions, we hope to foster a deeper understanding of the gut-kidney axis and its implications for kidney transplantation.
We invite contributions from researchers investigating various aspects of the gut-kidney axis, including but not limited to the role of gut microbiota in shaping the immune response post-transplant, the impact of dietary interventions on gut health and transplant outcomes, and the mechanistic pathways through which gut-derived signals influence renal immunology.
We welcome original research articles, reviews, and perspective pieces that contribute to this evolving field. Manuscripts should be well-documented and adhere to the journal’s submission guidelines, focusing on innovative findings and novel insights into the interactions between gut health and kidney transplantation.
The interplay between the gut and kidney has garnered significant attention in recent years, particularly concerning its role in modulating the immune response in kidney transplant recipients. The gut is home to a complex ecosystem of microbiota and immune cells that contribute to systemic immunity and may influence transplant outcomes.
Understanding the gut-kidney axis is crucial for developing strategies to enhance graft survival and improve the overall health of kidney transplant recipients. This Research Topic aims to elucidate the mechanisms by which gut immune cells and microbiota affect the immune microenvironment in kidney transplant recipients. We seek to address critical questions regarding the relationship between gut health and transplant outcomes, including how alterations in gut microbiota may predispose recipients to acute rejection or chronic allograft dysfunction.
Additionally, we encourage investigations into potential therapeutic interventions targeting the gut microbiome or immune modulation strategies that could optimize immune responses and enhance transplant success. By assembling a collection of studies that highlight these interactions, we hope to foster a deeper understanding of the gut-kidney axis and its implications for kidney transplantation.
We invite contributions from researchers investigating various aspects of the gut-kidney axis, including but not limited to the role of gut microbiota in shaping the immune response post-transplant, the impact of dietary interventions on gut health and transplant outcomes, and the mechanistic pathways through which gut-derived signals influence renal immunology.
We welcome original research articles, reviews, and perspective pieces that contribute to this evolving field. Manuscripts should be well-documented and adhere to the journal’s submission guidelines, focusing on innovative findings and novel insights into the interactions between gut health and kidney transplantation.
Keywords: Gut-Kidney Axis, Immune Microenvironment, Gut Microbiota, Kidney Transplant, Immune Cells
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
