About this Research Topic
Aura is a transient neurological disturbance that affects about one third of migraine sufferers, and manifests as a variety of sensory and visual symptoms. Although most evidence supports the genesis of aura from cortical spreading depression —a wave of electrical activity followed by a period of neuronal suppression— much remains to be understood about aura pathophysiology, and our understanding of this remarkably complex phenomenon is constantly evolving.
Aside from the aura itself, migraine can often be accompanied by a plethora of sensory phenomena, including and not limited to: photophobia, photic allodynia, cranial and generalized allodynia, changes in vision, visual snow, tinnitus, vertigo, and diffuse pain. These conditions and comorbidities can occur both interictally and during the attack phase and can have significant implications both in the diagnosis and management of patients.
This special issue aims to bring together cutting-edge research, clinical experiences and expert reviews exploring neurological mechanisms, clinical features, diagnosis, and therapeutic strategies related to aura and sensory phenomena in migraine.
By uniting diverse perspectives from basic science, clinical practice, and experimental models, we hope to foster innovative insights in phenotype definition and clinical variabilities, frequent clustering with other diseases or rare, peculiar comorbidities, patients’ management as well as pharmacological and non-pharmacological treatments of these disabling migraine phenomena, also considering the current scenario of CGRP targeting therapies.
We hope that contributions will ultimately improve a comprehensive understanding of these conditions.
Article types include original research, letters, reviews, case series, literature reviews, systematic review, meta-analyses.
Aside from the aura itself, migraine can often be accompanied by a plethora of sensory phenomena, including and not limited to: photophobia, photic allodynia, cranial and generalized allodynia, changes in vision, visual snow, tinnitus, vertigo, and diffuse pain. These conditions and comorbidities can occur both interictally and during the attack phase and can have significant implications both in the diagnosis and management of patients.
This special issue aims to bring together cutting-edge research, clinical experiences and expert reviews exploring neurological mechanisms, clinical features, diagnosis, and therapeutic strategies related to aura and sensory phenomena in migraine.
By uniting diverse perspectives from basic science, clinical practice, and experimental models, we hope to foster innovative insights in phenotype definition and clinical variabilities, frequent clustering with other diseases or rare, peculiar comorbidities, patients’ management as well as pharmacological and non-pharmacological treatments of these disabling migraine phenomena, also considering the current scenario of CGRP targeting therapies.
We hope that contributions will ultimately improve a comprehensive understanding of these conditions.
Article types include original research, letters, reviews, case series, literature reviews, systematic review, meta-analyses.
Keywords: aura, migraine, visual snow, allodynia, photophobia, sensory phenomena, pathophysiology, comorbidities.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
