Bone and cartilage regeneration plays a crucial role in sports medicine and physical activity, as it seeks to address the urgent need for effective treatments for injuries, degenerative diseases, and congenital defects. Traditional methods such as autografts and allografts are limited by donor site morbidity, scarcity, and the risk of immune rejection. Furthermore, current standard treatments are unlikely to offer a complete cure for these conditions, necessitating the development of innovative therapeutic strategies. The rapid progress in medical technology and the continuous expansion of medical research fields have further fueled interest in this area. As a result, there has been a significant focus on the development of biomaterials and the use of advanced technologies such as 3D printing to create more effective solutions for tissue regeneration.
Recent advancements in medical technology and materials science have spurred interest in creating more effective solutions for tissue regeneration. Biomaterials and 3D printing technologies have emerged as promising approaches, offering the potential to revolutionize the treatment of sports-related injuries. The hierarchical and complex structures of bone and cartilage display different mechanical properties in various regions, which makes it difficult to replicate such architecture. Cartilage is particularly challenging to replicate due to its avascular nature and limited self-repair ability.
The development of biomaterials that closely resemble the extracellular matrix, promote cell attachment, and integrate seamlessly with native tissue is a promising strategy for regenerating damaged tissues. These materials, which can be natural or synthetic, have unique properties that allow them to interact with biological tissues to support, repair, or replace damaged structures. Additionally, 3D printing allows for precise positioning of cells and biomaterials, enabling the creation of scaffolds that accurately replicate the complex architecture of bone and cartilage. By customizing the scaffold to match the patient’s anatomical structure, it becomes possible to improve both the integration and functionality of the regenerated tissue.
The objective of this Research Topic is to foster an interdisciplinary dialogue on the applications and advancements in the domain of multifunctional biomaterials, encompassing a diverse range of material types within the context of sports and physical activity. We invite high-caliber research articles and review pieces that will exemplify and catalyze ongoing endeavors to comprehend the realm of multifunctional biomaterials and sophisticated processing technology for bone and cartilage regeneration. Also, how biomaterials can be utilized in sports medicine to prevent and rehabilitate injuries is a topic of significant interest.
We extend a warm invitation to authors to submit original and review articles on the topic of bone and cartilage regeneration, with a particular emphasis on its applications in sports and physical activity. The scope of this topic is broad, including but not limited to:
• Natural and synthetic materials for the regeneration of bone and cartilage
• Multifunctional materials regulate endogenous cellular metabolism and differentiation for the regeneration of bone and cartilage
• Spatiotemporal control of bioactive factors delivery for bone and cartilage regeneration
• Emerging fabrication technologies for scaffold development in bone and cartilage regeneration.
By addressing these areas, we hope to contribute to the development of innovative treatments that enhance the recovery and performance of athletes and active individuals, ultimately improving outcomes in sports medicine and physical activity-related healthcare.
Keywords:
Biomaterials, 3D printing, Bone, cartilage, tissue regeneration, sports medicine, physical activity
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Bone and cartilage regeneration plays a crucial role in sports medicine and physical activity, as it seeks to address the urgent need for effective treatments for injuries, degenerative diseases, and congenital defects. Traditional methods such as autografts and allografts are limited by donor site morbidity, scarcity, and the risk of immune rejection. Furthermore, current standard treatments are unlikely to offer a complete cure for these conditions, necessitating the development of innovative therapeutic strategies. The rapid progress in medical technology and the continuous expansion of medical research fields have further fueled interest in this area. As a result, there has been a significant focus on the development of biomaterials and the use of advanced technologies such as 3D printing to create more effective solutions for tissue regeneration.
Recent advancements in medical technology and materials science have spurred interest in creating more effective solutions for tissue regeneration. Biomaterials and 3D printing technologies have emerged as promising approaches, offering the potential to revolutionize the treatment of sports-related injuries. The hierarchical and complex structures of bone and cartilage display different mechanical properties in various regions, which makes it difficult to replicate such architecture. Cartilage is particularly challenging to replicate due to its avascular nature and limited self-repair ability.
The development of biomaterials that closely resemble the extracellular matrix, promote cell attachment, and integrate seamlessly with native tissue is a promising strategy for regenerating damaged tissues. These materials, which can be natural or synthetic, have unique properties that allow them to interact with biological tissues to support, repair, or replace damaged structures. Additionally, 3D printing allows for precise positioning of cells and biomaterials, enabling the creation of scaffolds that accurately replicate the complex architecture of bone and cartilage. By customizing the scaffold to match the patient’s anatomical structure, it becomes possible to improve both the integration and functionality of the regenerated tissue.
The objective of this Research Topic is to foster an interdisciplinary dialogue on the applications and advancements in the domain of multifunctional biomaterials, encompassing a diverse range of material types within the context of sports and physical activity. We invite high-caliber research articles and review pieces that will exemplify and catalyze ongoing endeavors to comprehend the realm of multifunctional biomaterials and sophisticated processing technology for bone and cartilage regeneration. Also, how biomaterials can be utilized in sports medicine to prevent and rehabilitate injuries is a topic of significant interest.
We extend a warm invitation to authors to submit original and review articles on the topic of bone and cartilage regeneration, with a particular emphasis on its applications in sports and physical activity. The scope of this topic is broad, including but not limited to:
• Natural and synthetic materials for the regeneration of bone and cartilage
• Multifunctional materials regulate endogenous cellular metabolism and differentiation for the regeneration of bone and cartilage
• Spatiotemporal control of bioactive factors delivery for bone and cartilage regeneration
• Emerging fabrication technologies for scaffold development in bone and cartilage regeneration.
By addressing these areas, we hope to contribute to the development of innovative treatments that enhance the recovery and performance of athletes and active individuals, ultimately improving outcomes in sports medicine and physical activity-related healthcare.
Keywords:
Biomaterials, 3D printing, Bone, cartilage, tissue regeneration, sports medicine, physical activity
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.