About this Research Topic
Gut dysbiosis, characterized by an imbalance in the gut microbiota, has been increasingly recognized as a crucial factor in the development and progression of various aging-related diseases. With aging, the gut microbiome undergoes significant changes, leading to a decline in microbial diversity and an increase in pathogenic bacteria. This dysbiosis contribute to chronic inflammation, metabolic disorders, frailty, and cognitive impairment, which are common in the elderly population. Moreover, recent studies have established a strong link between gut dysbiosis and the onset of age-related diseases such as Alzheimer's disease, Parkinson's disease, diabetes, kidney diseases, and cardiovascular disease. Understanding the complex interplay between gut microbiota and the aging process is essential for developing effective interventions to promote healthy aging and prevent age-related diseases.
The goal of this research topic on gut dysbiosis and aging diseases is to provide a comprehensive overview of the current research in this field and to highlight the potential therapeutic strategies targeting the gut microbiota. The issue aims to bring together interdisciplinary perspectives from experts in microbiology, immunology, geriatrics, and other related fields to explore the complex relationship between gut microbiota and aging-related diseases. By publishing high-quality original research articles, review articles, and case studies, the research topic seeks to advance our understanding of the pathogenesis of aging-related diseases and to identify potential targets for intervention. Ultimately, the goal of this special issue is to foster collaboration and promote innovative approaches to combat aging-related diseases through modulation of the gut microbiome.
The scope of this Research Topic includes, but is not limited to, the following themes:
-The relationship between gut microbiota composition and age-related diseases.
-The role of diet and lifestyle factors in shaping gut microbiota and their impact on aging and age-related diseases.
-The effects of antibiotics and other medications on gut microbiota and their potential to accelerate the aging process or increase the risk of age-related diseases.
-The potential of probiotics and prebiotics to mitigate the negative effects of gut dysbiosis on aging and age-related diseases.
-The mechanisms by which gut dysbiosis contributes to the development and progression of age-related diseases, including inflammation, oxidative stress, and immune system dysfunction.
-The use of advanced technologies such as metagenomics and metabolomics to study gut microbiota and their association with aging and age-related diseases.
The goal of this research topic on gut dysbiosis and aging diseases is to provide a comprehensive overview of the current research in this field and to highlight the potential therapeutic strategies targeting the gut microbiota. The issue aims to bring together interdisciplinary perspectives from experts in microbiology, immunology, geriatrics, and other related fields to explore the complex relationship between gut microbiota and aging-related diseases. By publishing high-quality original research articles, review articles, and case studies, the research topic seeks to advance our understanding of the pathogenesis of aging-related diseases and to identify potential targets for intervention. Ultimately, the goal of this special issue is to foster collaboration and promote innovative approaches to combat aging-related diseases through modulation of the gut microbiome.
The scope of this Research Topic includes, but is not limited to, the following themes:
-The relationship between gut microbiota composition and age-related diseases.
-The role of diet and lifestyle factors in shaping gut microbiota and their impact on aging and age-related diseases.
-The effects of antibiotics and other medications on gut microbiota and their potential to accelerate the aging process or increase the risk of age-related diseases.
-The potential of probiotics and prebiotics to mitigate the negative effects of gut dysbiosis on aging and age-related diseases.
-The mechanisms by which gut dysbiosis contributes to the development and progression of age-related diseases, including inflammation, oxidative stress, and immune system dysfunction.
-The use of advanced technologies such as metagenomics and metabolomics to study gut microbiota and their association with aging and age-related diseases.
Keywords: Gut dysbiosis, aging diseases, microbiome, intestinal flora, inflammation, immune system, chronic conditions, nutrition, dietary interventions.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
