New approaches in Tuberculosis Drug Discovery

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CORRECTION

Published on 05 Nov 2019

Corrigendum: A Nanostructured Lipid System to Improve the Oral Bioavailability of Ruthenium(II) Complexes for the Treatment of Infections Caused by Mycobacterium tuberculosis

Patricia B. da Silva
Eduardo Sinésio de Freitas
Mariana Cristina Solcia
Paula Carolina de Souza
Monize Martins da Silva
Alzir Azevedo Batista
Carlos E. Eismann
Ana Marta C. M. Rolisola
Amauri A. Menegário
2 more
Fernando R. Pavan

doi 10.3389/fmicb.2019.02517

2,754 views

CORRECTION

Published on 31 May 2019

Corrigendum: A Nanostructured Lipid System to Improve the Oral Bioavailability of Ruthenium(II) Complexes for the Treatment of Infections Caused by Mycobacterium tuberculosis

Patricia B. da Silva
Eduardo Sinésio de Freitas
Mariana Cristina Solcia
Paula Carolina de Souza
Monize Martins da Silva
Alzir Azevedo Batista
Carlos E. Eismann
Ana Marta C. M. Rolisola
Amauri A. Menegário
2 more
Fernando R. Pavan

doi 10.3389/fmicb.2019.01213

1,606 views

ORIGINAL RESEARCH

Published on 06 Dec 2018

A Nanostructured Lipid System to Improve the Oral Bioavailability of Ruthenium(II) Complexes for the Treatment of Infections Caused by Mycobacterium tuberculosis

Patricia B. da Silva
Eduardo Sinésio de Freitas
Mariana Cristina Solcia
Paula Carolina de Souza
Monize Martins da Silva
Alzir Azevedo Batista
Carlos E. Eismann
Ana Marta C. M. Rolisola
Amauri A. Menegário
2 more
Fernando R. Pavan

doi 10.3389/fmicb.2018.02930

3,077 views
4 citations

ORIGINAL RESEARCH

Published on 11 Sep 2018

Direct Growth Inhibitory Effect of Platelet Activating Factor C-16 and Its Structural Analogs on Mycobacteria

Muhammad S. Riaz
Anuvinder Kaur
Suha N. Shwayat
Shahriar Behboudi
Uday Kishore
Ansar A. Pathan

doi 10.3389/fmicb.2018.01903

2,743 views
6 citations

ORIGINAL RESEARCH

Published on 05 Sep 2018

Interfering With DNA Decondensation as a Strategy Against Mycobacteria

Enzo M. Scutigliani
Edwin R. Scholl
Anita E. Grootemaat
Sadhana Khanal
Jakub A. Kochan
Przemek M. Krawczyk
Eric A. Reits
Atefeh Garzan
Huy X. Ngo
4 more
Nicole N. van der Wel

doi 10.3389/fmicb.2018.02034

4,369 views
10 citations

ORIGINAL RESEARCH

Published on 21 Aug 2018

Primary Lung Dendritic Cell Cultures to Assess Efficacy of Spectinamide-1599 Against Intracellular Mycobacterium tuberculosis

Karen Santos
Pradeep B. Lukka
Anne Grzegorzewicz
Mary Jackson
Ashit Trivedi
Fernando Pavan
Marlus Chorilli
Miriam Braunstein
Anthony Hickey
1 more
Mercedes Gonzalez-Juarrero

doi 10.3389/fmicb.2018.01895

2,328 views
6 citations

REVIEW

Published on 19 Jul 2018

The Mycobacterial Membrane: A Novel Target Space for Anti-tubercular Drugs

Huan Chen
Samuel A. Nyantakyi
Ming Li
Pooja Gopal
Dinah B. Aziz
Tianming Yang
Wilfried Moreira
Martin Gengenbacher
Thomas Dick
Mei L. Go

doi 10.3389/fmicb.2018.01627

9,462 views
42 citations

ORIGINAL RESEARCH

Published on 12 Jul 2018

Identification of Novel Mycobacterial Inhibitors Against Mycobacterial Protein Kinase G

Yuichi Kanehiro
Haruaki Tomioka
Jean Pieters
Yutaka Tatano
Hyoji Kim
Hisashi Iizasa
Hironori Yoshiyama

doi 10.3389/fmicb.2018.01517

5,333 views
21 citations

REVIEW

Published on 03 Jul 2018

Challenging the Drug-Likeness Dogma for New Drug Discovery in Tuberculosis

Diana Machado
Miriam Girardini
Miguel Viveiros
Marco Pieroni

doi 10.3389/fmicb.2018.01367

7,843 views
88 citations

ORIGINAL RESEARCH

Published on 02 Jul 2018

Unprecedented in Vitro Antitubercular Activitiy of Manganese(II) Complexes Containing 1,10-Phenanthroline and Dicarboxylate Ligands: Increased Activity, Superior Selectivity, and Lower Toxicity in Comparison to Their Copper(II) Analogs

Pauraic McCarron
Malachy McCann
Michael Devereux
Kevin Kavanagh
Ciaran Skerry
Petros C. Karakousis
Ana C. Aor
Thaís P. Mello
André L. S. Santos
1 more
Fernando R. Pavan

doi 10.3389/fmicb.2018.01432

2,969 views
27 citations

REVIEW

Published on 01 May 2018

Is IQG-607 a Potential Metallodrug or Metallopro-Drug With a Defined Molecular Target in Mycobacterium tuberculosis?

Bruno L. Abbadi
Valnês da Silva Rodrigues-Junior
Adilio da Silva Dadda
Kenia Pissinate
Anne D. Villela
Maria M. Campos
Luiz G. de França Lopes
Cristiano V. Bizarro
Pablo Machado
1 more
Luiz A. Basso

doi 10.3389/fmicb.2018.00880

3,747 views
13 citations

ORIGINAL RESEARCH

Published on 09 Apr 2018

Naphthoquinone Derivatives as Scaffold to Develop New Drugs for Tuberculosis Treatment

Priscila C. B. Halicki
Laís A. Ferreira
Kelly C. G. De Moura
Paula F. Carneiro
Karina P. Del Rio
Tatiane dos S. C. Carvalho
Maria do C. F. R. Pinto
Pedro E. A. da Silva
Daniela F. Ramos

doi 10.3389/fmicb.2018.00673

4,605 views
30 citations

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Antimicrobials, Resistance and Chemotherapy

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Articles

Corrigendum: A Nanostructured Lipid System to Improve the Oral Bioavailability of Ruthenium(II) Complexes for the Treatment of Infections Caused by Mycobacterium tuberculosis

Corrigendum: A Nanostructured Lipid System to Improve the Oral Bioavailability of Ruthenium(II) Complexes for the Treatment of Infections Caused by Mycobacterium tuberculosis

A Nanostructured Lipid System to Improve the Oral Bioavailability of Ruthenium(II) Complexes for the Treatment of Infections Caused by Mycobacterium tuberculosis

Direct Growth Inhibitory Effect of Platelet Activating Factor C-16 and Its Structural Analogs on Mycobacteria

Interfering With DNA Decondensation as a Strategy Against Mycobacteria

Primary Lung Dendritic Cell Cultures to Assess Efficacy of Spectinamide-1599 Against Intracellular Mycobacterium tuberculosis

The Mycobacterial Membrane: A Novel Target Space for Anti-tubercular Drugs

Identification of Novel Mycobacterial Inhibitors Against Mycobacterial Protein Kinase G

Challenging the Drug-Likeness Dogma for New Drug Discovery in Tuberculosis

Unprecedented in Vitro Antitubercular Activitiy of Manganese(II) Complexes Containing 1,10-Phenanthroline and Dicarboxylate Ligands: Increased Activity, Superior Selectivity, and Lower Toxicity in Comparison to Their Copper(II) Analogs

Is IQG-607 a Potential Metallodrug or Metallopro-Drug With a Defined Molecular Target in Mycobacterium tuberculosis?

Naphthoquinone Derivatives as Scaffold to Develop New Drugs for Tuberculosis Treatment

Frontiers in Microbiology

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