About this Research Topic
The mouth and the body are not separated, and oral and systemic health have an unquestionable bidirectional relationship. This research topic focuses on exploring the mouth as a biosignature source for controlling and monitoring diseases from childhood to adulthood.
The mouth is a valuable source of biological material, including tongue/cheeks/palate scraps, saliva, biofilm, and crevicular fluid. Compared to blood samples, collecting oral material is easy, economical, minimally invasive, and avoids stress-related bias. Mouth elements could correlate with blood, particularly saliva, in lower concentrations. Notably, biosignatures can reach the oral cavity through serum ultrafiltration between cell junctions, passive diffusion mechanisms, and synthesis and secretion by saliva glands.
Subjects are stimulated to seek dental visits throughout the year to maintain good oral health. This allows dentists to collect oral material, enabling early detection of diseases, identifying those at risk, or referring to a physician in case of a common signature for systemic disease.
Scientific information on this topic would be useful in developing cross-disciplinary health promotion programs based on common risk approaches, helping to overcome the gap between oral and general health.
The following papers will be accepted: original research, mini-review, review, study protocol, brief research report, case report, perspective, general commentary, and opinion.
Find below the welcome themes:
- Investigations connecting oral and systemic pathologies;
- Studies examining any oral biological material (i.e., biofilm, saliva, crevicular fluid) as biosignature/biomarker for diseases;
- Papers assessing common oral risk indicators/factors in all age groups.
The mouth is a valuable source of biological material, including tongue/cheeks/palate scraps, saliva, biofilm, and crevicular fluid. Compared to blood samples, collecting oral material is easy, economical, minimally invasive, and avoids stress-related bias. Mouth elements could correlate with blood, particularly saliva, in lower concentrations. Notably, biosignatures can reach the oral cavity through serum ultrafiltration between cell junctions, passive diffusion mechanisms, and synthesis and secretion by saliva glands.
Subjects are stimulated to seek dental visits throughout the year to maintain good oral health. This allows dentists to collect oral material, enabling early detection of diseases, identifying those at risk, or referring to a physician in case of a common signature for systemic disease.
Scientific information on this topic would be useful in developing cross-disciplinary health promotion programs based on common risk approaches, helping to overcome the gap between oral and general health.
The following papers will be accepted: original research, mini-review, review, study protocol, brief research report, case report, perspective, general commentary, and opinion.
Find below the welcome themes:
- Investigations connecting oral and systemic pathologies;
- Studies examining any oral biological material (i.e., biofilm, saliva, crevicular fluid) as biosignature/biomarker for diseases;
- Papers assessing common oral risk indicators/factors in all age groups.
Keywords: Biosignatures, Oral-systemic health, Biomarkers, Saliva analysis, Disease monitoring
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
