Recent advancements in pharmaceutical sciences have introduced smart stimuli-responsive biomaterials, affording precise spatiotemporal control in therapeutic delivery. Known for adapting to various stimuli—such as pH changes, temperature, and biological signals—these materials optimize treatment efficacy directly at disease sites, benefiting oncology, regenerative medicine, and other complex conditions.
Incorporating a stimuli-responsive approach with nanostructured materials further enhances the versatility and effectiveness of these systems. Nanostructured biomaterials, with their inherent properties such as high surface area, tunable size, and modifiable surface characteristics, can be engineered to respond to specific stimuli, improving therapeutic outcomes and minimizing off-target effects. The integration of biomaterials with stimuli-responsive materials offers an exciting platform for developing next-generation drug delivery systems, diagnostic tools, and tissue engineering scaffolds that can revolutionize patient care.
This Research Topic seeks to highlight the latest innovations in the design, synthesis, and biomedical applications of smart, stimuli-responsive biomaterials. Special emphasis will be placed on the integration of nanotechnology to create hybrid systems with enhanced therapeutic or theranostic potential. From improving drug loading capacities to enabling precise targeting of diseased cells, these engineered biomaterials are at the forefront of personalized medicine. Furthermore, their multifaceted theranostic nature extends beyond drug delivery, providing novel diagnostics, imaging, and regenerative therapy solutions.
To harness and conglomerate the theranostic capabilities of nanostructured biomaterials, we invite contributions in the form of Original Research Articles, Reviews, Mini-Reviews, Systematic Reviews, Perspectives, Commentaries, Data Notes, and Technical Notes that break new ground in targeted delivery systems, diagnostics, and therapeutic mechanisms. Priority topics include, but are not limited to
• Innovative Polymeric and Hydrogel Systems: Exploring stimuli-responsive biomaterials with bioactive constituents for enhanced drug delivery.
• Targeted Drug Delivery via Functionalized Nanostructures: Enhancing bioavailability and precision in therapeutics.
• Surface Engineering for Cellular Targeting: Employing smart conjugations for pathogen-specific interactions.
• Multifunctional Theranostic Platforms: Integrating diagnostics with therapeutic functions for real-time monitoring.
• Regenerative Applications: Focusing on cellular matrices and scaffolds that promote growth and response to physiological cues.
We would like to acknowledge Sagnik Nag as Coordinator, and for his contribution to the preparation of this Research Topic.
Keywords:
Biomaterials, Nanomedicine, Nanostructures, Drug delivery, Theranostics, Regeneration
Surface engineering, Personalized therapy
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Recent advancements in pharmaceutical sciences have introduced smart stimuli-responsive biomaterials, affording precise spatiotemporal control in therapeutic delivery. Known for adapting to various stimuli—such as pH changes, temperature, and biological signals—these materials optimize treatment efficacy directly at disease sites, benefiting oncology, regenerative medicine, and other complex conditions.
Incorporating a stimuli-responsive approach with nanostructured materials further enhances the versatility and effectiveness of these systems. Nanostructured biomaterials, with their inherent properties such as high surface area, tunable size, and modifiable surface characteristics, can be engineered to respond to specific stimuli, improving therapeutic outcomes and minimizing off-target effects. The integration of biomaterials with stimuli-responsive materials offers an exciting platform for developing next-generation drug delivery systems, diagnostic tools, and tissue engineering scaffolds that can revolutionize patient care.
This Research Topic seeks to highlight the latest innovations in the design, synthesis, and biomedical applications of smart, stimuli-responsive biomaterials. Special emphasis will be placed on the integration of nanotechnology to create hybrid systems with enhanced therapeutic or theranostic potential. From improving drug loading capacities to enabling precise targeting of diseased cells, these engineered biomaterials are at the forefront of personalized medicine. Furthermore, their multifaceted theranostic nature extends beyond drug delivery, providing novel diagnostics, imaging, and regenerative therapy solutions.
To harness and conglomerate the theranostic capabilities of nanostructured biomaterials, we invite contributions in the form of Original Research Articles, Reviews, Mini-Reviews, Systematic Reviews, Perspectives, Commentaries, Data Notes, and Technical Notes that break new ground in targeted delivery systems, diagnostics, and therapeutic mechanisms. Priority topics include, but are not limited to
• Innovative Polymeric and Hydrogel Systems: Exploring stimuli-responsive biomaterials with bioactive constituents for enhanced drug delivery.
• Targeted Drug Delivery via Functionalized Nanostructures: Enhancing bioavailability and precision in therapeutics.
• Surface Engineering for Cellular Targeting: Employing smart conjugations for pathogen-specific interactions.
• Multifunctional Theranostic Platforms: Integrating diagnostics with therapeutic functions for real-time monitoring.
• Regenerative Applications: Focusing on cellular matrices and scaffolds that promote growth and response to physiological cues.
We would like to acknowledge Sagnik Nag as Coordinator, and for his contribution to the preparation of this Research Topic.
Keywords:
Biomaterials, Nanomedicine, Nanostructures, Drug delivery, Theranostics, Regeneration
Surface engineering, Personalized therapy
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.