About this Research Topic
Neuropathic pain is a chronic and debilitating condition that impacts around 10% of the population in both the United States and Europe. Despite advances in understanding the mechanisms of neuropathic pain, current therapeutic options remain largely ineffective for a significant portion of patients. Increasing evidence highlights the critical role of non-coding RNAs, in regulating gene expression associated with neuropathic pain. Dysregulation of lncRNAs is now recognized as a key factor contributing to nociceptive hypersensitivity under neuropathic conditions. Understanding the molecular mechanisms behind these dysregulations offers promising opportunities for developing novel therapeutic strategies to prevent or alleviate neuropathic pain.
role of non-coding RNAs in neuropathic pain. It questions whether modulation of these RNAs can yield targeted pain relief. This topic aims to elucidate the potential of non-coding RNAs for developing personalized neuropathic pain treatments by analyzing recent studies, including transcriptomic data and therapeutic implications. We invite submissions that provide novel insights into RNA-based therapies, RNA-pain pathway interactions, and innovative biomarkers for neuropathic pain management.
This Research Topic seeks contributions that examine non-coding RNAs' roles in neuropathic pain regulation and treatment. We invite studies on how altered non-coding RNA expression affects pain signaling, neuronal plasticity, and inflammation in neuropathic contexts. Submissions investigating the therapeutic implications of non-coding RNA targeting, including RNA therapies, gene editing, and modulation, are strongly encouraged.
We accept various manuscript types, such as original research, reviews, mini-reviews, clinical trials, and perspectives. Research on biomarker development, mechanistic insights, and transcriptomic analyses is especially welcome. Authors are urged to submit innovative research that enhances understanding of non-coding RNAs' potential in neuropathic pain management and treatment efficacy.
role of non-coding RNAs in neuropathic pain. It questions whether modulation of these RNAs can yield targeted pain relief. This topic aims to elucidate the potential of non-coding RNAs for developing personalized neuropathic pain treatments by analyzing recent studies, including transcriptomic data and therapeutic implications. We invite submissions that provide novel insights into RNA-based therapies, RNA-pain pathway interactions, and innovative biomarkers for neuropathic pain management.
This Research Topic seeks contributions that examine non-coding RNAs' roles in neuropathic pain regulation and treatment. We invite studies on how altered non-coding RNA expression affects pain signaling, neuronal plasticity, and inflammation in neuropathic contexts. Submissions investigating the therapeutic implications of non-coding RNA targeting, including RNA therapies, gene editing, and modulation, are strongly encouraged.
We accept various manuscript types, such as original research, reviews, mini-reviews, clinical trials, and perspectives. Research on biomarker development, mechanistic insights, and transcriptomic analyses is especially welcome. Authors are urged to submit innovative research that enhances understanding of non-coding RNAs' potential in neuropathic pain management and treatment efficacy.
Keywords: Non-Coding RNAs, Pain Mechanisms, Pain Management, Inflammation, Neuroglia, Cytokines, Chemokines
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
