About this Research Topic
Anemia remains a pervasive global health challenge, notably among children aged 6 months to 5 years, with disparities seen from less than 10% prevalence in developed regions to greater than 50% in developing areas like sub-Saharan Africa. This condition in children is influenced by a variety of factors, including nutritional deficiencies such as iron, folate, and vitamin B12, hemoglobinopathies, inherited red cell disorders, and chronic infections. These etiologies influence changes with geographical and socio-economic variations, pointing to the complexity of addressing childhood anemia effectively. Despite the high prevalence, significant gaps exist in our understanding and management of anemia, necessitating focused research and dialogue within the pediatric and hematology communities.
This Research Topic aims to clarify the outstanding issues surrounding anemia in children, enhance our comprehension of its definition, epidemiology, health impacts, etiology, pathophysiology, and clinical manifestations. It seeks to foster the development of novel diagnostic and therapeutic strategies that address the varied causes of anemia across different global contexts. Additionally, this topic intends to dissect the specific issues related to each cause of anemia, including genetic red cell disorders and dietary shortfalls, aiming to catalyze advancements in the field.
To gather further insights into the multifaceted nature of childhood anemia, we welcome submissions of original research, review articles, brief reports, case series, and case reports. We encourage submissions focused on, but not limited to, the following themes:
• National and regional epidemiology and burden of childhood anemia
• Nutritional anemias including iron deficiency, megaloblastic anemia, and deficiencies in folate and vitamin B12
• Hemoglobinopathies like thalassemia and sickle cell disease
• Inherited red cell membranopathies such as spherocytosis and elliptocytosis, and enzymopathies including glucose 6-phosphate dehydrogenase and pyruvate kinase deficiencies
• Other rare inherited anemias
• Anemia associated with chronic diseases and infections
This Research Topic aims to clarify the outstanding issues surrounding anemia in children, enhance our comprehension of its definition, epidemiology, health impacts, etiology, pathophysiology, and clinical manifestations. It seeks to foster the development of novel diagnostic and therapeutic strategies that address the varied causes of anemia across different global contexts. Additionally, this topic intends to dissect the specific issues related to each cause of anemia, including genetic red cell disorders and dietary shortfalls, aiming to catalyze advancements in the field.
To gather further insights into the multifaceted nature of childhood anemia, we welcome submissions of original research, review articles, brief reports, case series, and case reports. We encourage submissions focused on, but not limited to, the following themes:
• National and regional epidemiology and burden of childhood anemia
• Nutritional anemias including iron deficiency, megaloblastic anemia, and deficiencies in folate and vitamin B12
• Hemoglobinopathies like thalassemia and sickle cell disease
• Inherited red cell membranopathies such as spherocytosis and elliptocytosis, and enzymopathies including glucose 6-phosphate dehydrogenase and pyruvate kinase deficiencies
• Other rare inherited anemias
• Anemia associated with chronic diseases and infections
Keywords: Anemia, Red cell disorders, Hemoglobinopathy, Iron deficiency, Thalassemia, Membranopathy, Sickle cell disease, Megaloblastic anemia, Chronic infections, Red cell aplasia
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
