About this Research Topic
Microbiota therapeutics also known as microbial therapy involve using microorganisms or their components to improve human health by targeting the gut microbiota. Microbiota therapeutics represent a rapidly evolving field and are gaining attention from researchers and health professionals. Recent technological advancements promise to expand treatment options and improve outcomes for diverse health conditions linked to the microbiota. Synthetic biology offers a powerful toolkit to engineer probiotics or microbial consortia for targeted therapeutic effects. As research progresses, the scope of synthetic biology in microbiota therapeutics is broad. It holds significant potential for transforming how we approach the treatment of various diseases and the maintenance of human health. Innovative research in this field could lead to innovative treatments and personalized healthcare solutions.
The enormous metabolic potential of gut microbes and their role in human health has developed a scope of microbiota-based therapies to cure human illnesses. Microbiota-based therapies gained the attention of researchers, medical professionals, and biotechnological industries. Synthetic biology offers promising avenues for microbiome therapeutics. Synthetic biology allows the engineering of individual probiotic strains or restructuring the whole microbial communities to restore health. Microbes could be genetically manipulated to produce beneficial compounds, enhance probiotic properties, or enable targeted interactions with host cells. It also includes designing synthetic consortia of microbes that work synergistically to exert therapeutic effects for better health. This approach could potentially replace or supplement traditional pharmaceutical treatments. Conclusively, synthetic biology holds the potential to revolutionize microbiome therapeutics for personalized medicine and optimizing treatment regimens. Through this special issue, research and development in this field will be showcased to escalate the pace of research to comprehend the concept of microbiome diagnostics and therapeutic interventions.
In this research topic, we welcome manuscripts in the form of original research, reviews, case studies, and novel technological interventions primarily focusing on synthetic biology and genomics to develop efficient microbiota therapeutics for better healthcare.
The key focus areas of the present issues are:
- Microbiota therapies for disease management
- Customized probiotics and microbiota modulation
- Microbial engineering for drug production
- Designing and development of synthetic consortia
- Human microbiota-based sensors and disease diagnostics
- Human-microbial interactions in health and diseases
- Regulating human- microbial interactions for better health
- Microbiota therapeutics integration with other therapeutic modalities
- Technological and scientific innovations in synthetic microbiology
- Ethical and regulatory issues
The enormous metabolic potential of gut microbes and their role in human health has developed a scope of microbiota-based therapies to cure human illnesses. Microbiota-based therapies gained the attention of researchers, medical professionals, and biotechnological industries. Synthetic biology offers promising avenues for microbiome therapeutics. Synthetic biology allows the engineering of individual probiotic strains or restructuring the whole microbial communities to restore health. Microbes could be genetically manipulated to produce beneficial compounds, enhance probiotic properties, or enable targeted interactions with host cells. It also includes designing synthetic consortia of microbes that work synergistically to exert therapeutic effects for better health. This approach could potentially replace or supplement traditional pharmaceutical treatments. Conclusively, synthetic biology holds the potential to revolutionize microbiome therapeutics for personalized medicine and optimizing treatment regimens. Through this special issue, research and development in this field will be showcased to escalate the pace of research to comprehend the concept of microbiome diagnostics and therapeutic interventions.
In this research topic, we welcome manuscripts in the form of original research, reviews, case studies, and novel technological interventions primarily focusing on synthetic biology and genomics to develop efficient microbiota therapeutics for better healthcare.
The key focus areas of the present issues are:
- Microbiota therapies for disease management
- Customized probiotics and microbiota modulation
- Microbial engineering for drug production
- Designing and development of synthetic consortia
- Human microbiota-based sensors and disease diagnostics
- Human-microbial interactions in health and diseases
- Regulating human- microbial interactions for better health
- Microbiota therapeutics integration with other therapeutic modalities
- Technological and scientific innovations in synthetic microbiology
- Ethical and regulatory issues
Keywords: Microbiota Therapeutics, Probiotics, Prebiotics, Fecal Microbiome Transplantation, Synthetic biology, Microbiota Engineering, Precision Medicine
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
